I seems absolutely normal. Ever after program has being re-installed many settings are still kept intact (applies to most Windows programs).
Your problem is unrelated to the subject of this thread hence in the future it's better to create your own separate thread. It looks like you having some weird configuration issue limited to your particular machine, hence unlikely any trader (=non-tech) on this forum would be able to help. I would assume your broker would be the only party interested and capable of trying to resolve your configuration issues (as it requires the knowledge of both the broker and the software, their tech would probably need to remote-connect to your PC).
Why do you feel the need to delete the layout if you like it? Anyway most professional trading platforms allow saving hotkey configuration in a separate file (independent of layout).
I emailed myself a copy of it. Already deleted it off my PC. Someone recommend I delete it. Not sure if the Layout is cause-of-the-issue. Not sure how I would save the hotkeys in a separate file in Sterling Trader Pro.
I am thinking about joining a prop firm that uses Sterling pro, but am curious if they allow Market on open limit orders to NYSE and NASDAQ. I know they did along time ago, but wasnt sure now.