The Deniers told us COVID doesn't hurt Children

Discussion in 'Politics' started by gwb-trading, Aug 16, 2021.

  1. Cuddles

    Cuddles

    Or in your rush to post anything COVID, you slipped and did not grasp the subject of the article. As you've done before
     
    #461     Jul 20, 2022
  2. gwb-trading

    gwb-trading


    Let's take a look at a large scale study with a control group regarding children, vaccination, and Omicron.


    BNT162b2 Vaccine Effectiveness against Omicron in Children 5 to 11 Years of Age
    https://www.nejm.org/doi/full/10.1056/NEJMoa2205011
    June 29, 2022

    Abstract
    Background
    Limited evidence is available on the real-world effectiveness of the BNT162b2 vaccine against coronavirus disease 2019 (Covid-19) and specifically against infection with the omicron variant among children 5 to 11 years of age.

    Methods
    Using data from the largest health care organization in Israel, we identified a cohort of children 5 to 11 years of age who were vaccinated on or after November 23, 2021, and matched them with unvaccinated controls to estimate the vaccine effectiveness of BNT162b2 among newly vaccinated children during the omicron wave. Vaccine effectiveness against documented severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and symptomatic Covid-19 was estimated after the first and second vaccine doses. The cumulative incidence of each outcome in the two study groups through January 7, 2022, was estimated with the use of the Kaplan–Meier estimator, and vaccine effectiveness was calculated as 1 minus the risk ratio. Vaccine effectiveness was also estimated in age subgroups.

    Results
    Among 136,127 eligible children who had been vaccinated during the study period, 94,728 were matched with unvaccinated controls. The estimated vaccine effectiveness against documented infection was 17% (95% confidence interval [CI], 7 to 25) at 14 to 27 days after the first dose and 51% (95% CI, 39 to 61) at 7 to 21 days after the second dose. The absolute risk difference between the study groups at days 7 to 21 after the second dose was 1905 events per 100,000 persons (95% CI, 1294 to 2440) for documented infection and 599 events per 100,000 persons (95% CI, 296 to 897) for symptomatic Covid-19. The estimated vaccine effectiveness against symptomatic Covid-19 was 18% (95% CI, −2 to 34) at 14 to 27 days after the first dose and 48% (95% CI, 29 to 63) at 7 to 21 days after the second dose. We observed a trend toward higher vaccine effectiveness in the youngest age group (5 or 6 years of age) than in the oldest age group (10 or 11 years of age).

    Conclusions
    Our findings suggest that as omicron was becoming the dominant variant, two doses of the BNT162b2 messenger RNA vaccine provided moderate protection against documented SARS-CoV-2 infection and symptomatic Covid-19 in children 5 to 11 years of age. (Funded by the European Union through the VERDI project and others.)

    (Full study at above url -- many pages)
     
    #462     Jul 20, 2022
  3. gwb-trading

    gwb-trading

    Another study with large scale results regarding children, vaccination, and Covid during the Omicron period -- is the following study from Argentina also involving millions of children with a control group.

    Effectiveness of BBIBP-CorV, BNT162b2 and mRNA-1273 vaccines against hospitalisations among children and adolescents during the Omicron outbreak in Argentina: A retrospective cohort study
    https://www.thelancet.com/journals/lanam/article/PIIS2667-193X(22)00133-8/fulltext

    Summary
    Background
    Although paediatric clinical presentations of COVID-19 are usually less severe than in adults, serious illness and death have occurred. Many countries started the vaccination rollout of children in 2021; still, information about effectiveness in the real-world setting is scarce. The aim of our study was to evaluate vaccine effectiveness (VE) against COVID-19-associated-hospitalisations in the 3–17-year population during the Omicron outbreak.

    Methods
    We conducted a retrospective cohort study including individuals aged 3–17 registered in the online vaccination system of the Buenos Aires Province, Argentina. mRNA-1273 and BNT162b2 were administered to 12–17-year subjects; and BBIBP-CorV to 3–11-year subjects. Vaccinated group had received a two-dose scheme by 12/1/2021. Unvaccinated group did not receive any COVID-19 vaccine between 12/14/2021 and 3/9/2022, which was the entire monitoring period. Vaccine effectiveness (VE) against COVID-19-associated hospitalisations was calculated as (1-OR)x100.

    Findings
    By 12/1/2021, 1,536,435 individuals aged 3–17 who had received zero or two doses of SARS-CoV-2 vaccines were included in this study. Of the latter, 1,440,389 were vaccinated and 96,046 not vaccinated. VE were 78.0%[68.7–84.2], 76.4%[62.9–84.5] and 80.0%[64.3–88.0] for the entire cohort, 3–11-year (BBIBP-CorV) subgroup and 12–17 (mRNA vaccines) subgroup, respectively. VE for the entire population was 82.7% during the period of Delta and Omicron overlapping circulation and decreased to 67.7% when Omicron was the only variant present.

    Interpretation
    This report provides evidence of high vaccine protection against associated hospitalisations in the paediatric population during the Omicron outbreak but suggests a decrease of protection when Omicron became predominant. Application of a booster dose in children aged 3–11-year warrants further consideration.

    (Much more at above url)
     
    #463     Jul 20, 2022
  4. Tsing Tao

    Tsing Tao

     
    #464     Jul 25, 2022
  5. gwb-trading

    gwb-trading

    #465     Aug 1, 2022
  6. gwb-trading

    gwb-trading

    #466     Aug 19, 2022
  7. gwb-trading

    gwb-trading

    Yet... there are still Covid-deniers out there pushing every day that Covid does not harm children. They whine the body count is not high enough -- while ignoring the many children with Long Covid and children who were severely ill in hospitals.

    Long Covid: Girl, 10, struggles to walk and talk
    https://www.bbc.com/news/uk-wales-62041613
     
    #467     Aug 20, 2022
  8. Tsing Tao

    Tsing Tao

     
    #468     Sep 1, 2022
  9. Tsing Tao

    Tsing Tao

    Say what you want about the man, but this was true.

     
    #469     Sep 2, 2022
    smallfil likes this.
  10. #470     Oct 6, 2022