Statins

Discussion in 'Health and Fitness' started by Pekelo, Jul 21, 2017.

  1. In the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT), the effect of LIPITOR on fatal and non-fatal coronary heart disease was assessed in 10,305 hypertensive patients 40–80 years of age (mean of 63 years), without a previous myocardial infarction and with TC levels ≤251 mg/dL (6.5 mmol/L). Additionally, all patients had at least 3 of the following cardiovascular risk factors: male gender (81.1%), age >55 years (84.5%), smoking (33.2%), diabetes (24.3%), history of CHD in a first-degree relative (26%), TC:HDL >6 (14.3%), peripheral vascular disease (5.1%), left ventricular hypertrophy (14.4%), prior cerebrovascular event (9.8%), specific ECG abnormality (14.3%), proteinuria/albuminuria (62.4%).

    In this double-blind, placebo-controlled study, patients were treated with anti-hypertensive therapy (Goal BP <140/90 mm Hg for non-diabetic patients; <130/80 mm Hg for diabetic patients) and allocated to either LIPITOR 10 mg daily (n=5168) or placebo (n=5137), using a covariate adaptive method which took into account the distribution of nine baseline characteristics of patients already enrolled and minimized the imbalance of those characteristics across the groups. Patients were followed for a median duration of 3.3 years.

    LIPITOR significantly reduced the rate of coronary events [either fatal coronary heart disease (46 events in the placebo group vs. 40 events in the LIPITOR group) or non-fatal MI (108 events in the placebo group vs. 60 events in the LIPITOR group)] with a relative risk reduction of 36% [(based on incidences of 1.9% for LIPITOR vs. 3.0% for placebo), p=0.0005 (see Figure 1)].


    WAIT........you took a supposed high risk group of people which you assume would have a high incidence of coronary heart disease and in the group of people who got a PLACEBO, there were 46 PEOPLE who had a coronory event? 46 out of 5,168 or .008%!!!

    So if I did simply research where I collected 5,168 men who were older and had some health issues such as diabetes, smoking, family history of CHF and raised cholesterol and .008% of them had a coronary heart disease event, that indicates significance and that billions of dollars should be spent on a medication with bad side effects without $1 spent on diet and lifestyle changes?

    How many of the 46 had a CHD event because of their weight, diet and lifestyle? Was never accounted for. 40 in the Lipitor group by the way....any way to know if the 6 person difference is solely atributable to cholesterol lowering without taking into account whether they were smoking, overweight or had a family history?

    This study is shit.
     
    #71     Apr 12, 2019
  2. So you're saying published cardiologist with 30+ years experience running her own clinic at a major hospital don't do their own research. You know better because you read an article available to the public. How thorough. Another internet MD giving advance, you know how absurd you come across?
     
    #72     Apr 12, 2019
  3. You advised everyone to listen to their doctors, I commented that most GPs are getting recommendation from the pharma sales people. Then you come back with some bull shit about a 30+ year cardiologist?

    And you were also giving advance..or is the word advice
     
    #73     Apr 12, 2019
  4. nkhoi

    nkhoi


    I take 1 or 2 teaspoon of Terrasoul Superfoods Organic Reishi Mushroom Powder daily,
    my level dropped to 60 when taking Crestor + Mushroom Powder together.
    Note: mushroom powder makes you sleep like a chicken and also lower your blood pressure. If your blood pressure is low DON'T take it.

    For good fat I take OmegaVia EPA 500 Omega-3 Fish Oil. High-Purity EPA-Only, the bad thing is the level will drop if I stop taking it.
     
    Last edited: Apr 15, 2019
    #74     Apr 12, 2019
    schweiz likes this.
  5. I never ever said gp, only specialist! You assumed I ment gp when i said doctor. You know cardiologist are Specialist, they are doctors also. But you knew that, right? whew...
     
    #75     Apr 12, 2019
  6. Pekelo

    Pekelo

    Here is a trick question to ask your cardiologist:

    Are eggs good for us or not? :)
     
    #76     Apr 15, 2019
  7. I did ask, she said in moderation. Egg whites are best ...
     
    #77     Apr 15, 2019
  8. schweiz

    schweiz

    And which color is best? Brown or white? And why?
     
    #78     Apr 16, 2019
  9. From what I’ve heard, the body responses to statins by producing more cholesteral. Keep your blood sugar low through diet and regular excercise and your odds for avoiding cardiovascular issues go up.
     
    #79     Apr 17, 2019
  10. Pekelo

    Pekelo

    Speaking of blood sugar... Berberine is one of the few supplements that has very comparable results to prescription drugs. It lowers blood sugar AND cholesterol, beside other good things like BP lowering, and helping with weight control.

    Since this is the statin thread, Berberine lowered TC by 19% in trials.
     
    #80     Apr 17, 2019
    nkhoi likes this.