Under Joe Biden's leadership, scientists use pandemic killer against top killer disease: https://www.rush.edu/news/could-cov...ke protein of,findings in the journal Cancers. Could COVID-19 Hold a Cancer Cure? RUSH researchers find virus’ spike protein reduces lung tumors in lab study The notorious spike protein of SARS-CoV-2, the virus that causes COVID-19, caused lung cancer cells to die in laboratory studies conducted by researchers at RUSH University Medical Center, who recently published their findings in the journal Cancers. The discovery raises the possibility that the pandemic that has afflicted the globe for three years might also yield a treatment for lung cancer, and perhaps other cancers as well. The coronavirus infects human cells when its spike protein, known as S1, attaches to a molecule on the cell surface called angiotensin-converting enzyme 2. ACE2, as it’s called for short, is a beneficial enzyme that plays a key role in the regulation of blood pressure and other cellular processes. The level of ACE2 also increases in people with cancer, including lung cancer, and studies have found that modifying ACE2 levels may help control lung cancer growth. The involvement of ACE2 in both cancer progression and coronavirus infection prompted the RUSH researchers to investigate the use of the spike protein against the disease. “It is always important to find mechanisms to stimulate cancer cell death and stop the progression of cancer,” said Kalipada Pahan, PhD, the Floyd A. Davis professor of neurology at RUSH Medical College and lead investigator of this study. He adds that anecdotal cases of people with lung cancer that improved after they developed and recovered from COVID-19 also suggest the coronavirus’ potential as an unlikely ally against cancer. Cancer is the number two cause of death in U.S., second only to heart disease, according to Centers for Disease Control and Prevention. Despite recent advances in treatment, lung cancer is by far the leading cause of cancer deaths throughout the world — more than 130,000 people die of it each year in the U.S. alone. Lung cancer accounts for 25% of cancer deaths in the U.S., more than deaths from colon cancer, breast cancer and prostate cancer combined. Using a commercially available cloned version of the spike protein, Pahan and his colleagues first tested the protein’s effect on the most treatment-resistant and deadliest form of lung cancer, non-small cell lung cancer, or NSCLC. In petri dishes, they combined the spike protein with human NSCLC cell cultures and measured the resulting levels of the proteins and molecules involved in cancer cell growth, compared with untreated NSCLC cells. They found that in the NSCLC cells combined with S1, the spike protein induced apoptosis — the programmed death of cells that’s a routine process in an organism’s development. Accordingly, spike treatment decreased the levels of a molecule known as Bcl-2 that is needed for cell survival, and it increased the level of a molecule named BAD that is required for cell death. “Cancer cells do not die from apoptosis due to high level of Bcl-2 and low levels of BAD,” Pahan said. The researchers then examined the results of administering the spike protein to mice with established lung cancer. One group of mice received the spike protein in a mixture with saline solution that was sprayed into their nostrils every other day, while a control group received normal saline solution as a placebo. After four weeks of spike protein treatment, the mice were euthanized and autopsied. The researchers found the number and size of tumors decreased in the mice that received the spike protein, and higher levels of tumor cell death, compared to the control group. “If these results are replicated in lung cancer patients, it would uncover an encouraging avenue of treatment of this devastating disease.” Pahan said. “Intranasal spike S1 protein could be used for late-stage lung cancer when there’s no other therapy to stop the progression.” Pahan and his team currently are seeking partners to study the use of the spike protein in clinical trials of human patients with lung cancer. Since most of the widely available vaccines for COVID-19 target the spike protein, one of the important questions future studies will need to answer is whether vaccination diminishes the protein’s efficacy as a cancer intervention. Other researchers involved in this study are Monica Sheinin and Brian Jeong from the Graduate College of RUSH University and Ramesh K. Paidi, PhD, from the medical college’s Department of Neurological Sciences.
Donald promised, Joe delivers. What Trump promised, Biden seeks to deliver in his own way https://apnews.com/article/inflatio...omy-business-e3f4d51b28d1c2ceab4766147406cf4c Donald Trump pledged to fix U.S. infrastructure as president. He vowed to take on China and bulk up American manufacturing. He said he would reduce the budget deficit and make the wealthy pay their fair share of taxes. Yet after two years as president, it’s Joe Biden who is acting on those promises. He jokes that he’s created an “infrastructure decade” after Trump merely managed a near parody of “infrastructure weeks.” His legislative victories are not winning him votes from Trump loyalists or boosting his overall approval ratings. But they reflect a major pivot in how the government interacts with the economy at a time when many Americans fear a recession and broader national decline. Gone are blanket tax cuts. No more unfettered faith in free trade with non-democracies. The Biden White House has committed more than $1.7 trillion to the belief that a mix of government aid, focused policies and bureaucratic expertise can deliver long-term growth that lifts up the middle class. This reverses the past administration’s view that cutting regulations and taxes boosted investments by businesses that flowed downward to workers. With new laws in place, Biden is taking the gamble that the federal bureaucracy can successfully implement and deliver on his promises, including after he leaves office. That is a tricky spot, as Trump himself learned that global crises such as a pandemic can quickly ruin the foundations of an economic agenda, causing businesses and voters to shift priorities. There are few guarantees that the economy behaves over 10 years as government forecasts expect, while Biden’s policies will likely be challenged by the new Republican majority in the House. Biden and his team say Americans are already seeing the upside with announcements for new computer chip plants and some 6,000 infrastructure projects under way. “There’s an industrial strategy that actually uses public investments to drive more private capital and more innovation in the historical tradition of everybody from Alexander Hamilton to Abraham Lincoln to John F. Kennedy,” said Brian Deese, director of the White House National Economic Council. “The outcomes speak for themselves.” Trump’s supporters see little overlap with Biden, even though the funding for infrastructure, computer chip production and scientific research was passed along bipartisan lines. “The Biden administration agenda is 180 degrees different,” said James Carter, a policy director at the America First Policy Institute. “More regulation, higher taxes, no border control and a war on fossil fuels. It’s two different administrations with two different approaches. One is free market, the other is big government.” The current and former president seem almost bound together in the public arena. On the August eve of Biden signing into law $280 billion for semiconductors and research, FBI agents raided Trump’s home to retrieve classified documents, overshadowing the White House event. Similarly, Biden called out Trump as a threat to democracy ahead of November midterm elections, while Republicans campaigned by hammering the president for troubling levels of inflation. Biden aides are quick to say that the president is fulfilling his own campaign promises, rather than honoring pledges made by Trump. But one of Biden’s first moves as president in 2021 was to provide $1,400 in direct payments to Americans as part of his coronavirus relief package. Along with the $600 in payments in a pre-Biden relief package, the sum matched the $2,000 that Trump called for in the twilight of his presidency, though he could not get it through Congress. “I would want to avoid the premise that somehow what Joe Biden has done was take Donald Trump’s ideas and enact them into law,” Deese said. “What President Biden has done is taken the campaign agenda that he campaigned on and actually delivered on it.” For all of that, Americans are giving Biden low marks on the economy. Inflation has come down from a 40-year peak this summer, but consumer prices are still 7.1% higher from a year ago. The Federal Reserve is raising its benchmark interest rate to lower inflation, something that its own projections show will cause unemployment to rise in the next year. Three in four Americans describe the economy as poor, with nearly the same percentage saying the U.S. is on the wrong track, according to a new poll by The Associated Press and NORC Center for Public Affairs Research. Biden is asking for patience. “I know it’s been a rough few years for hardworking Americans and for small businesses as well,” Biden said in Tuesday remarks about inflation. “But there are bright spots all across America where we’re beginning to see the impact of our economic strategy, and we’re just getting started.” Trump supporters blame Biden’s separate $1.9 trillion in coronavirus relief for sparking the inflation, although it contained roughly $400 billion worth of the direct payments that former president said Americans should receive. They argue that the U.S. economy would be stronger if Biden took steps such as allowing all businesses to fully expense their investments in new equipment, instead of providing targeted support to the technology and clean energy sectors. But even excluding the recession induced by the pandemic, Trump’s economic record was far from sterling as the promised growth never materialized. Manufacturers began to slash jobs in 2019 before the coronavirus spread, instead of the steady resurgence promised by Trump. Annual budget deficits worsened under Trump, but they have improved under Biden as pandemic aid has wound down. Biden is telling Americans that his policies will strengthen the U.S. economy over the next decade. His $52 billion for computer chip production has led to a series of factory groundbreakings in Arizona, Idaho, New York, North Carolina, Ohio and Texas that will take years to complete. The idea is that government aid reduces risk and makes it easier for these companies to invest in areas where global demand exceed available supplies. Chris Miller, a Tufts University professor and author of the book “Chip War,” said the incentives are only a fraction of the cost of building the plants. Miller said the benefits of the investments will spill over to the companies that sell raw materials to chipmakers as well as possibly for the makers of autos, electronics and household appliances that increasingly rely on chips. “The chips funding makes clear that there will be meaningfully more fab construction and chip output in the U.S.,” he said, “so for suppliers to the chip industry, they have more clarity that demand for their products will be larger than it otherwise would have been, incentivizing them to invest too.” For all the economic concerns, manufacturing has improved under Biden as factory employment totals 12.9 million jobs, the most since December 2008. Just as Biden has boosted domestic investment, he also expanded the Trump administration’s efforts to compete with China and kept his predecessor’s tariffs. The Biden administration has restricted the export of advanced computer chips and semiconductor equipment, arguing on national security grounds that China is using this technology for surveillance and hypersonic missiles. It’s also formed deeper partnerships with Australia, Japan, South Korea and several European countries to counter China’s rising influence. Kurt Campbell, Biden’s “Asian tsar” on the White House National Security Council, said that many of the initiatives pursued by Trump’s State Department on China have been “followed on” during Biden’s presidency, saying at an April panel that “in many respects, that’s the highest tribute” to the previous administration. But Steve Yates, a senior fellow at the America First Policy Institute and former president of Radio Free Asia, said that Biden has not shown that he’s placed the same emphasis on China as Trump. Yates cited as evidence that Biden’s national security strategy identifies the U.S. as having a shared interest with China in addressing climate change. He said that China will exploit that priority to their advantage as Biden’s willingness to cooperate on climate change will prevent him from confronting Beijing as Trump did. “We just have a weakened hand,” Yates said.
Biden is always trying to copy Trump. I wonder why? Because Trump is a great President. Biden not so much. lol
More of Biden copying Trump Biden, in newly released Nov. 4 video, says Iran nuclear deal 'dead' Biden adds that end of JCPOA nuclear deal is a 'long story' and White House officials 'are not going to announce it'
No.As stated blacks usually support Dem Presidents by 90%, only 45% support Biden running again and I have to question what the hell is wrong with them considering Biden gave zero fucks about the black community that gave him the Dem nomination and presidency after he got elected.
They must be smart enough to realize the dangers of fascism given they're first in line and can't afford virtue signaling from a place of privilege.