Start with the papers on "insulin autoinmune syndrome", and follow the trail to more recent research, then you may have to call a few doctors and biochemists and talk to them about what they have in the pipeline for publishing. You may or may not reach me. Who knows?. I will probably be busy trading, if you do.
http://care.diabetesjournals.org/content/34/9/e146.long One case in Italy? I am not stating it's not causal, but man, that's rare. It's in all likelihood inborn and not acquired (idiopathic and recessive).
True Dat! on creatine and protein. Long term creatine use will screw up your kidney functions... as for protein intake for athletes : http://perfecthealthdiet.com/2011/03/protein-for-athletes/
I lift pretty heavy, and stopped all protein supplementation with zero effect on performance and recovery. Prior, I supplemented with 50 grams of whey protein twice daily (morning and post workout) plus additional protein from solid food. My personal opinion is protein supplementation is meant for elite performance athletes and body builders who are physically at their maximum, and/or using anabolic steroids. I supplemented with protein for years; fell victim to the hype and worry of 'what if' i stop. Won't I lose all my gains??!!? lol It had zero effect on my strength, recovery, gains, and overall lean muscle mass. It's not worth the health risk or cost, imo. Even just 80-120 grams of protein a day in solid food is more then enough. If you're craving or worried, just eat more solid food. Preferably some protein with CARBS (rice, potatoes or oatmeal). Carbs have gotten a bad rap. Sure, weight loss is accelerated on a low/no carb diet. But for the gym, strength and building muscle mass....EAT YOUR CARBS. For bulking, it works great. I eat five potatoes during every post workout meal. Or half a box of spaghetti noodles. That's where most of our strength comes from. I know this because low carb diets sap strength (I get weaker on them). This is all anecdotal but makes sense. Really, all a guy has to do is eat the largest meal of the day, post workout. Eat clean until your satiated, and that's it. No powders, pills etc. That simple. At least for me.
Do you have a link to any studies showing long term creatine and/or protein use by healthy individuals will cause kidney damage? I've read a lot on this and can't recall reading anything supporting what you said. I would be interested in looking at any information you have.
http://www.ncbi.nlm.nih.gov/pubmed/15273072 Anyway, you will see a rise in BUN/creatinine. You will have levels 100x normal if supplementing, and it's cleared by the kidneys. That's it's job. Part of the rise is increased activity (renal met of the substance) and the rest is well, damage.
I'm not a huge Ray Peat fan but here's more on optimal protein consumption. http://peatarian.com//39553/critical-review-series-optimal-protein-intake-recommends