San Diego is great. I'm originally from northern CA but moved back to SD from NYC for 2 years recently. (I'm now back in NY for personal reasons) .. I'm really only familiar with everywhere from La Holla north to Downtown. (La Holla, Pacific Beach, Mission Beach, Ocean Beach, Downtown) You really can't go wrong as long as you have decent judgement when finding your place of residence. Also some really good traders live there.