In reality, the executives & directors (regardless of the 10b5-1 plans) not only posses, but also influence the disclosure of material inside information. Moreover, they know of details about the potential length of every process within their company or with their regulators, which are almost impossible to be available to other investors unless you call or email their Investor Relations and specifically ask for them, e.g. how long will early stage testing take? How long does it take you to measure testing results, consolidate them, etc... But they are playing the by the book and doing nothing against the law, so they can't be charged with any wrongdoing.