study shows no benefit of using chloroquine on Covid patients requiring oxygen: https://www.medrxiv.org/content/10.1101/2020.04.10.20060699v1.full.pdf
and this as well today --- Hydroxychloroquine does not clear coronavirus https://www.foxnews.com/science/hyd...navirus-but-can-alleviate-symptoms-study-says A study of COVID-19 patients in China who received hydroxychloroquine showed the anti-malarial drug did not clear the patients of the virus. "The overall 28-day negative conversion rate was not different between [standard-of-care] plus [hydroxychloroquine and standard-of-care] group (Kaplan-Meier estimates 85.4% versus 81.3%, P=0.341)," researchers wrote in the study. "Negative conversion rate at day 4, 7, 10, 14 or 21 was also similar between the two groups. No different 28-day symptoms alleviation rate was observed between the two groups." The research consisted of 150 patients who were hospitalized with COVID-19, the disease caused by the novel coronavirus. It has not yet been peer-reviewed and was published earlier this month on the medXiv repository. (More at above url)
‘Comprehensive’ study by French doctors and scientists does ‘not support’ the use of hydroxychloroquine to treat coronavirus: report https://www.alternet.org/2020/04/co...droxychloroquine-to-treat-coronavirus-report/ Expert immunologist Dr. Anthony Fauci (who is part of President Donald Trump’s coronavirus task force) and Peter Navarro (one of Trump’s top economic advisers) recently had a heated argument in the White House Situation Room over the benefits of hydroxychloroquine. Trump and Navarro have been aggressively touting that anti-malaria drug as a possible treatment for coronavirus, while Fauci is much more skeptical and has stressed that a lot more research needs to be conducted. And a new study by French doctors and scientists shows why Fauci remains skeptical: according to the study, hydroxychloroquine might have no benefits at all where COVID-19 is concerned. The South China Morning Post’s Stephen Chen reports that the French scientists’ research “compared more than 180 patients — some receiving hydroxychloroquine treatment and others who were not treated with the drug — and found their outcomes were almost identical.” The study, according to Chen, was conducted by “doctors and scientists from 12 hospitals and public research institutes across France” and was the “most comprehensive” so far on the possible benefits of hydroxychloroquine as an anti-coronavirus treatment. The website MedRxiv.org quotes the researchers as saying of the study, “These results do not support the use of hydroxychloroquine in patients hospitalized for documented Sars-CoV-2-positive hypoxic pneumonia.” The COVID-19 outbreak has turned out to be the deadliest pandemic the world has suffered since the Spanish flu outbreak of 1918. According to researchers at John Hopkins University in Baltimore, COVID-19 had killed more than 129,000 worldwide as of early Wednesday afternoon, April 15. That included at least 26,119 people in the United States (now the coronavirus epicenter), 21,067 in Italy, 18,579 in Spain and 15,729 in France. And because COVID-19 is a new disease, there is no vaccination against it. Health experts have been estimating that a COVID-19 vaccine is at least a year away. Chen, in his South China Morning Post article, explains why the French study was more “comprehensive” than previous ones. “They pulled the medical records from four hospitals in France of 181 patients of similar gender, age and health conditions,” Chen observes. “All the patients required oxygen because of lung infections caused by the virus.” According to the authors of the French study, “In conclusion, we found that hydroxychloroquine did not significantly reduce admission to ICU or death at Day Seven after hospital admission, or acute respiratory distress syndrome in hospitalized patients with hypoxemic pneumonia due to COVID-19. These results are of major importance and do not support the use of hydroxychloroquine in patients hospitalized for a documented Sars-CoV-2 pneumonia.”
It feels like if these characters would be hoping this doesn't work just to spite Trump. They would prefer thousands of people to die and thousands of businesses to go bankrupt hoping Trump loses re-election.
I would prefer that the medical community and public health agencies provide guidance on the usage of medicine to treat a disease. The use of a particular experimental medicine should not be driven by politicians and media pundits hyping it. In the case of hydroxychloroquine the hyping by Trump and others has caused several problems: it caused a shortage of hydroxychloroquine to be available for Lupus patients due to the run on the drug. It caused multiple deaths due to people taking the drug without proper medical guidance. In fact the number of deaths caused by people taking hydroxychloroquine will probably be greater than the number "saved" by hydroxychloroquine use for COVID-19 (the proven number is zero) It caused a misapplication of money away from trials of more promising treatments into evaluating hydroxychloroquine. Probably increasing the death rate from COVID-19 due to the other more promising treatments being ignored in a critical period of the pandemic.
I read the south china post article its a really screwed up study. on one hand.. the south china post says... "An uncontrolled study by a research team in Marseille, France, involving 26 patients found 100 per cent viral clearance in nose swabs in six patients treated by a combination of hydroxychloroquine and antibiotics, raising hope for the drug." Then later the article says "Among the patients who took hydroxychloroquine upon admission, 20.5 per cent had entered the intensive care unit or had died within a week. Among the patients who did not take the drug, the rate of ICU admission or mortality within a week was 22.1 per cent. The researchers said statistically there was no difference between the two groups. “In conclusion, we found that hydroxychloroquine did not significantly reduce admission to ICU or death at day seven after hospital admission, or acute respiratory distress syndrome in hospitalised patients with hypoxemic pneumonia due to Covid-19,” the authors said." --- Why can't they tell us about hydroxy and a zpack or hydroxy and zinc? I don't see anyone saying hydroxy works by itself.
Stop trolling DNC points. The number of people that have been saved by the use of this medicine is impossible to count. https://thehill.com/opinion/healthc...ine-could-cure-trump-derangement-syndrome?amp
Yeh. I dunno. I am just saying, as I have said in previous posts, that the advocates (I am an observer of all approaches, and don't have a dog in the fight other than to keep this dog and others alive) of the hydroxy/ zpac regimen state that it is a three-legged stool where you need all three elements. The hydroxy to move the zinc ion into the cell, and the azithro - which is both an anti-viral and anti-bacterial- to work against the virus and the pneumonia that tends to rear up as the immune system is weakened by the virus. I just want to increase the speed, precision, and efficiency by which the four or five approaches (remsdesvir, hyrdroxychloriquine, convalescent antibody, etc, etc) are examined and either advanced or dismissed. It doesnt help that those looking at the hydroxy regimen keep mixing and matching the elements included in the methodology. Right now, if someone put a gun to my head and said I could choose any treatment method that I wanted if I developed covid I would probably say that I would want resdemsivir at the onset, and if I were still struggling in a week, then I would want to add in antibody transfusions. Might change my mind next week. I am just following this in real time. I will continue to follow and root for the hydroxy regimen along with the others until I see a study that includes all three of the elements that the advocates claim are effective. When i see that, then I will form an opinion from there. In regard to Trump, I cheer for his advocacy and support for getting approaches examined and available to the public without being blocked by bureaucracy. Beyond that though I am not cheering for a specific drug. Just find out what works and send me some of dat.