“No hospitalizations or deaths” in J&J trail. Great news. Still want to see the participant profiles though.
Have Moderna or Pfizer published their stats with the Brazilian or S.African strains? All I’ve heard is they may not be as effective and they were working on a booster shot for future strains.
Did a quick DDG search, lots of articles give the same spin but no one gives specifics. Wonder why? Moderna. ........... While the study showed no changes immune response to the U.K. variant compared to the original coronavirus, the vaccine produced a weaker immune response to the South African variant. Stéphane Bancel, chief executive officer of Moderna, said "out of an abundance of caution," the company is developing a booster dose of the COVID-19 vaccine that could combat the South African variant and future emerging ones. https://www.usatoday.com/story/news...-against-uk-south-africa-variants/6698624002/ Pfizer ...... Pfizer/BioNTech’s coronavirus vaccine is only slightly less effective against the super-infectious South African variant, according to a lab study by the jab makers. Even with the slight reduction in efficacy, the research strongly suggests the vaccine will still be able to kill off the new strain before it can cause serious illness. https://www.usatodaysun.com/pfizer-says-covid-vaccine-works-against-south-african-super-strain/
Just to shamelessly reply to my own post, I just heard that J and J is in fact doing a study on administering their vaccine as a 2 dose vaccine to see if that boosts the effectivity. I also, I continue to not join with those who dismiss it as "useless" based on the 66% per cent overall effectivity. The overall effectivity rate - as neurtralizing, immediate knock out, total prevention vaccine was 66% but the overall effectivity in preventing hospitalizations and deaths was 100%. So, as always I caution against the binary stuff where a vaccine is either classified as good or totally useless. Depends on how you define "effective" as we have already overdiscussed many times. Keeping a person from dying even if they get sick is a plenty good thing to do, and is useful, not "useless."
I think Pfizer and Moderna state they are about 50% on the 1st jab. Israelis stats Pfizer came in well below that on 1 shot, something like 33%. https://news.yahoo.com/israel-warning-single-dose-pfizer-124313138.html
My elderly aunt got the Pfizer in Ireland, her nursing home newsletter said 33 percent for the first. Perhaps that is age adjusted as it can't be as effective in the very elderly.
I don’t want to cast the J&J vaccine on the trash pile. Specially when the storage and shipping protocols are normal vs the mRNA’s. If a booster can put them up in the 80-90% they have a winner. No one wants to admit it yet, but it’s looking like boosters are coming for Pfizer and Moderna to stay on top of the new emerging strains as well. I think a lot of folks, hoping not but figured that might be the case.
Fauci was saying it this morning on TV, they were saying it on Irish TV in July/Aug. Simply too many infected due to selfishness and disinformation so more mutants but.. Its not a fast mutating virus, and no virus has faced this level of focus. I'd expect to see the end of it within three to four years. That said, fantastic capacity to terrorise the world with this by storing live samples and waiting. The vaccine makers need to light footed with slight mods as Faucci said.