Woooo... Median age of hospitalized vaccinated patients: 64 Median age of hospitalized unvaccinated patients: 49 https://www.cdc.gov/mmwr/volumes/70/wr/mm7034e5.htm?s_cid=mm7034e5_w
I've been watching this Covid Vaccination and Not Vaccinated statistics very closely since the first month they begin to keep the statistics. The numbers are so convincingly in favor of the population that's vaccinated...its just as amazing to know how many out there that are still not vaccinated have such a statistical disadvantage at being Hospitalized, ICU admission, or Death. Unfortunately, there are one too many none Americans at this forum posting their misinformation of other countries at a North American forum when we all know that here in North America... Most of our Hospitalizations, ICU admissions, and Deaths are those not vaccinated. wrbtrader
Johnson & Johnson booster shot prompts large increase in immune response, company says https://www.wral.com/johnson-johnso...ase-in-immune-response-company-says/19841831/ Booster doses of Johnson & Johnson's one-shot coronavirus vaccine generated a big spike in antibodies, the frontline immune system defenses against infection, the company reported Wednesday. People who received a booster six to eight months after their initial J&J shots saw antibodies increase nine-fold higher than 28 days after the first shot, Johnson & Johnson said. The data comes from two Phase 2 studies conducted in the United States and Europe, the company said in a statement. Some of the 2,000 or so people in the studies got booster doses six months after their first doses of J&J's Janssen vaccine. "New interim data from these studies demonstrate that a booster dose of the Johnson & Johnson COVID-19 vaccine generated a rapid and robust increase in spike-binding antibodies, nine-fold higher than 28 days after the primary single-dose vaccination," the company said in its statement. "We have established that a single shot of our COVID-19 vaccine generates strong and robust immune responses that are durable and persistent through eight months. With these new data, we also see that a booster dose of the Johnson & Johnson COVID-19 vaccine further increases antibody responses among study participants who had previously received our vaccine," Dr. Mathai Mammen, global head of research and development for Janssen, said in a statement. J&J said it was in discussions with the US Food and Drug Administration, US Centers for Disease Control and Prevention, European Medicines Agency, World Health Organization and other health authorities about the need for offering a booster dose of the Janssen vaccine. "We look forward to discussing with public health officials a potential strategy for our Johnson & Johnson COVID-19 vaccine, boosting eight months or longer after the primary single-dose vaccination," Mammen added. Many people who received the J&J vaccine have been clamoring for information about whether they will need a booster shot. US federal government officials have said they are preparing to start offering a booster dose to people who got Moderna's or Pfizer's Covid-19 vaccine after data showed boosters can amp up the antibody response -- and after studies started showing an uptick in infections in both vaccinated and unvaccinated people. The more transmissible Delta variant is partly to blame, experts say, as is a waning immune response. The Janssen vaccine was authorized at the end of February, more than two months after Moderna's and Pfizer's vaccines were authorized. About 14 million Americans have received the J&J vaccine, according to the CDC. Dr. Dan Barouch, a vaccine researcher at Beth Israel Deaconess Medical Center and Harvard Medical School who is not involved in the two clinical studies but is helping study J&J vaccines, said the findings support getting a booster shot, but only after a delay. "The boost at six months is going to look very impressive and substantially greater than what has already been reported in terms of the two month boost, and that is significant because it, in my opinion, the boost should not be at two months, but it really should be at six months or later," Barouch told CNN. Neither of the studies looked at real-world efficacy, so the company has not demonstrated that people who get boosters will be less likely to become infected or to develop severe disease. But researchers are beginning to agree that antibody levels do indicate immune protection. The Johnson & Johnson vaccine is made differently from Pfizer's and Moderna's. Those two vaccines use messenger RNA or mRNA, encased in little lipid particles, to carry instructions to the body to start an immune response. The Janssen vaccine uses a crippled common cold virus called an adenovirus to carry in similar instructions. There had been worries that a booster dose of such a viral vector vaccine might not work effectively because of the possibility the body would generate an immune response against the vector, also. "There was a theoretical concern that the generation of anti-vector antibodies by the first shot could impede the use of it again," Barouch said. "I think these data put that to rest." Federal health officials have said they believe a booster dose of the Janssen vaccine will be needed at some point. "I'm quite certain that the FDA, CDC, NIH, White House will use these data to likely justify or recommend a booster for J&J-vaccinated people, probably with a second shot of J&J," Barouch said.
I wonder how this would work as a booster for mRNA vaccines (which antibodies do they measure?). I've considered J&J as a booster and to add broad spectrum protection & not just for spike protein antibodies...thinking being, having better protection against upcoming variants.
I was always under the belief that vaccines teach your immune system to build specific antibodies by introducing either a weakened/dead pathogen or in the case of mRNA’s a portion for the body to identify. Obviously, immediately after the shot your body will produce antibodies but it’s the ability of the immune system to remember and build later when reinfected, which is the goal. Polio vaccines for example, after the series I doubt the body keeps making antibodies years later, it’s remembered by the immune system to make in case it comes in contact in the future???? I can understand a variant specific booster, just boosting the alpha version not so much. Edit, imo the J&J is a better choice, it was tested against the African and Brazilian variants, offering a wider range of protection.
Don't try and introduce a useful understanding of science and how things work to fearful lefties. Their reptile minds will not accept the idea that a healthy immune system may not need to spike antibodies for each new resistant variant that comes along 6 Mos after the manufacturers begin to see the variant appear. They would rather mandate this stupidity for everyone high risk and low so they feel better...even if their actions will almost inevitablely risk a massive problem for more than the just high risk. They don't even notice that some experts are advising biden to hold off on pushing boosters on the low risk.
Fast-Track Emergency Use Approval of the NOVAVAX NVX-CoV2373 COVID-19 Vaccine Others are unwilling to take the medical risks of new mRNA technologies or simply want to take a vaccine that uses a more traditional protein subunit form. Sign the petition https://www.change.org/p/united-states-food-and-drug-administration-fast-track-emergency-use-approval-of-the-novavax-nvx-cov2373-covid-19-vaccine?