large study finds that (hydroxy)chloroquine killing more than it "cures"

Discussion in 'Politics' started by destriero, May 22, 2020.

  1. gwb-trading

    gwb-trading

    There are many other recent studies posted than the one from Surgisphere. Your claim seems to be that if the Surgisphere study cannot produce backing data then all the studies on the face of the earth are not valid. That simply is not so.
     
    #141     Jun 7, 2020
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  2. gwb-trading

    gwb-trading

    Does hydroxychloroquine prevent COVID-19? Health care workers sought for Duke study.
    https://www.newsobserver.com/news/coronavirus/article243363141.html

    More than 800 health care workers have enrolled in a study based at Duke University to determine whether the antimalarial drug hydroxychloroquine can help ward off COVID-19, and organizers are looking for more volunteers.

    Participants in the clinical trial are drawn from a pool of people who have enrolled in The Healthcare Worker Exposure Response and Outcomes (HERO) Registry. Also based at Duke, The HERO Registry includes more than 13,600 health care workers in all 50 states, including more than 1,000 in North Carolina.

    The registry was created in March as a place where health care workers could share information and their experiences from the front lines of the coronavirus outbreak. Members are also given the opportunity to take part in clinical trials, which this summer will likely include studies of some of the first vaccines against coronavirus, said Dr. Adrian Hernandez, lead investigator of the HERO research program and head of the Duke Clinical Research Institute where the registry is based.

    Hernandez said health care workers are motivated to help find new ways to treat or prevent COVID-19.

    “They are personally worried about their own health,” he said. “But what has really hit them is they’re really worried about their families and protecting their families.”

    So far, the only study drawing volunteers from the HERO Registry involves hydroxychloroquine or HCQ, which is used to treat malaria and autoimmune diseases such as rheumatoid arthritis and lupus.

    The drug has received lots of attention from the public and the press after President Donald Trump endorsed it as a way to prevent coronavirus infection, then disclosed last month that he was taking it for that reason. The Food and Drug Administration has cautioned against using HCQ to treat COVID-19 unless administered in a hospital or as part of a clinical trial because of a risk of heart rhythm problems.

    Interest in hydroxychloroquine has spawned dozens of clinical trials to test the drug alone or in combination with other medications, including the antibiotic azithromycin. While most trials are still underway, researchers in the United Kingdom announced Friday that they were halting a study involving nearly 4,700 people after their early results showed hydroxychloroquine provided no benefit.

    Participants in the HERO Registry’s study must enroll at one of 40 sites around the country, including Duke, UNC Chapel Hill and Wake Forest Baptist Health in Winston-Salem. They are given either hydroxychloroquine or a placebo for 30 days and complete online surveys about their health, mood and potential exposure to coronavirus. They’re also tested for COVID-19 before and after the trial.

    The study, like the registry itself, is open to all sorts of people who work in health care. That includes doctors, nurses, therapists and paramedics but also people who transport patients, prepare and serve food or clean rooms in hospitals, clinics and nursing homes.

    “We’re asking all people who serve in all types of healthcare settings to join,” Bridget Thomas, who manages the HERO-HCQ trial at Wake Forest, said in a statement. “We’re seeking healthcare workers from all environments — including hospitals, outpatient and urgent care clinics, nursing homes, and in-home nursing care — to join the HERO community.”

    Organizers of the hydroxychloroquine trial had at one point hoped to enroll 15,000 workers. Hernandez said they may not need that many to get effective results and said they continue to look for volunteers. To enroll in the HERO Registry and get more information about the hydroxychloroquine trial, go to heroesresearch.org/.
     
    #142     Jun 8, 2020
  3. LacesOut

    LacesOut

    How can this Yale epidemiologist possibly have a job tomorrow when he says that Hydroxychloroquine can save lives if given as a prophylactic??

     
    #143     Jul 21, 2020
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  4. Bugenhagen

    Bugenhagen

    What's with his hair? I immediately don't trust a man who has hair like that.

    So what he is saying is give people azithromycin or doxycycline and "probably" zinc.. Why probably if the hydroxychloroquine is ineffective without it? This I recall from a recent article he published.

    Or could it be that azithromycin / doxy help prevent the initial infection in the throat engulfing the lungs by killing opportunistc infections and surpressing a cytokine storm and the HCL is an anti-inflammatory, one that could be replaced with any other that does not have the QT issues combined with azithromycin?

    Basically you don't need the HCL but it suits some to keep it in the mix...

    I'm still taking HCL for my knee, helping but after having to adjust the interval twice, I have to say the large doses are concerning.
     
    Last edited: Jul 22, 2020
    #144     Jul 22, 2020
  5. easymon1

    easymon1

    intracellular zinc de-activates viral replication.
    gettin it in there is the crux of the biscuit.
    healthy enhancement of that process is the goal.
    qed
     
    #145     Jul 22, 2020
  6. easymon1

    easymon1

    intracellular zinc is the whole point, allowing deactivation of viral replication.
    zinc in the bloodstream is not effective, gotta get the zinc into the cells, that's the purpose of the hydro...
    if there's another method, that's safer, then check it out.
    oh, and don't be over 90, in a nursing home in new york.
     
    #146     Jul 22, 2020
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  7. smallfil

    smallfil

    Remember too that doctors on the front lines have these various medications in their desk drawers if they needed it. The same goes for their family members. It is an open secret that some doctors have used these same drugs as a prophylactic to prevent them catching the Corona Virus. When your job involves treating numerous Corona Virus infected patients daily, you would be a fool not to protect yourself. Each person is different so, a doctor is best judge on what medical course to take. However, doctors have noted the use of steroids, remdesivir, hydrochloroguine, azithromycin have had good results and cured patients. These are the doctors on the frontlines that are saying these things. I would trust them more than a so called medical expert earning six figures, seated in his cushy office, running his computer studies and telling us how many are going to die and how we should handle the Corona Virus? Now, who is going to lie and who is going to tell you the truth?
     
    #147     Jul 22, 2020
  8. LacesOut

    LacesOut

    Uh it’s always been about the combination of ZPak, HCL and zinc. Always. It works, according to this. But because OrangeManBad and it’s low cost....must tell the world it can’t work.
     
    #148     Jul 22, 2020
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  9. Bugenhagen

    Bugenhagen

    HCL is not generally low cost, Cl is. I can buy 20 CL for Literally 60c retail at the pharmacy, in a retail blister pack box. HCL is over 60 bucks US. Its probably hundreds in the US of course. Your conspiracy fails a bit there.

    You have a market of billions of doses and you can already make it.. But.. You decide to piss that away for some future drug where you face other competition. Near all drugs are cheap to make.

    The concern has been HCL combined with the ZPak altering the heart QT in combo. There are safer, very cheap, alternative ionophires. Also it really does very little in vivo.

    The reality is just like abortion, the right does not want to solve this but drag it out as a party talking point.

    I betcha that the ZPak alone is fine as a prophylactic. Take some vitamins.
     
    Last edited: Jul 22, 2020
    #149     Jul 22, 2020
  10. LacesOut

    LacesOut

    $0.37 per 200mg tablet (100 tabs) for HCL in the US.
    https://www.drugs.com/price-guide/hydroxychloroquine

    and it’s not the right but the leftards and policy makers and ‘muh science’ people who have binned the HCL because OrangeManBad. It’s just that simple. Trump cannot be right. At all costs. Even if it means lives.
     
    #150     Jul 22, 2020
    smallfil likes this.