Some of these hydroxy doses that they are using on patients are pretty small too so there is a lot that needs to be learned about dosing. Many of the docs are using something like 200 mg twice a day. But they are prescribing more like 1000 mg or more a day, long-term, for malaria users. Probably the lower dose is the way to go for covid except wayyyyyyyyyyyyyyy earlier in the game. There are lots and lot of drug that effective early on in smaller doses but are very ineffective at stopping a disease after it is full blown. Just sayin that part of the mentality among those who are finally loosening up on the use of hydroxy is based on "okay, I am all in favor of it experimentally but only for the sickest of the patients." But that mentality is the problem. It's like saying "we are going to have clinical trials on a new antibiotic but only going to use it on people who have developed gangrene." Helloooooo.. You probably could have prevented that gangrene with a drop of iodine at the right time. And from there one of hundreds of known antibiotics would work in the early stages. But full blown gangrene? Too much pressure to put on the drugs that would have worked earlier. Just sayin that the next move that the opponents will go for is to say that clinical trials show that it is only marginally effective in studies of ICU patients but that is probably not where hydroxy does its best work, if it does work. Dr. Fauci does great research but we are talking battlefield medicine here. I get his perspective and standards and it is highly desirable in his lane in life which is a lab. But if he were in some village in Africa where covid was breaking out and there was a whole supply of hydroxy in reach because it is being used in the region to fight malaria, I cannot not see him using it on a sick covid patient unless it went through his clinical trials. In battlefield medicine you have some frigging duty to be able to look a family in the eye and say that you tried everything. Yes the scammers and snake oil types need to be kept out of the process and there needs to be at least a reasonable basis for trying an approach even it does not work, but hydroxy meets that standard. The dems are gunning for dead americans and to see Trump fail. They are toxic to the country, some of the alleged dems here are actually in shit-hole countries right now and are not Americans. If hydroxy poops out and kills ten thousand people they will be as happy as clams at high tide.
I hear ya, but I also see a certain win-win dynamic shaping up. Everyone knows that the Holy Grail is for a vaccine and that this pandemic will spawn a whole new wave of research and pharmaceuticals not only for the covid but for other diseases that can benefit from the research on covid (just as we are also using the learnings from HIV and H1N1 on covid). Plus. There will be a YUGE effort to move drugs being made in China back to the U.S. So there is a HUGE gravy train lying ahead for U.S pharmaceutical companies far, far beyond just this hyrdroxy thing. Hydroxy is not even remotely the only game in town for what they are interested in. And hydroxy will probable be very helpful but it is not like it is going to cure or preven the condition or the next ones like it. I say this could be "win-win" because I see some of the pharmaceutical companies acting as though they realize that looking good by coughing up their supplies of hydroxy and ramping up for more is the way to curry favor with Trump and the American public at little cost to them, to set themselves up for all the other business long term. This is no time for them to be doing something that looks ugly. As we just saw happen with 3M's gouging and shipping medical supplies out of the country. Nope. The smart ones know they gotta work to help toss Trump his hydroxy bone because when Daddy is happy lots of them are going to be happy. If not, well then, not so much.
To start I have to give a shout out to Dr. Seheult with the Medcram folks, he’s been giving very good info via his YouTube channel. He’s been well ahead on the information curve with very accurate scientific explanations pertaining to Covid and treatments/preventative measures. According to the studies/links he references the effects of hydroxychloroquine stay in the bloodstream upwards to 14 days after dosage. Standard dosage was 400mg twice first day, 200 mg twice daily for 4 days. One dose should clear an individual and take them past a quarantine point. It’s my understanding that some medical centers now are prescribing their nurses, doctors the meds in a preventative fashion. If that’s the case they should be cycled every 3rd week. I agree early dosing would be better, instead of waiting for the patient to exhibit critical symptoms. There’s probably a supply issue at the moment prompting this. My concern is robbing the immune system of a chance to identify the virus and build any type of immunity if we’re just pouring it down our throats in prevention. There is a fine line here, as the virus seems to have the ability to mask itself from our early immune defenses, one minute your fine, actually been infected walking around feeling healthy for a few days, then 24 hours later your in the hospital for the 20% that need a hospital. Ideally, imo, you should wait till symptoms present themselves and then start the treatment but how do you balance that with the possibility of spreading? Still a lot to learn. What I’d like to see is Trump use the Defense Act and force production of the drug here. Im still waiting for the Quercetin stats to publish from the Canadian team in China. French team stating there’s an arthritic drug that is more effective that Chloroquine. My bad, will have to go back and find the drug listed. Edit, March 27, 2020 Update 8: While we are all talking about anti-malaria drugs hydroxychloroquine and chloroquine, Italian doctors said that Tolicizumab, a drug used to treat moderate to severe rheumatoid arthritis, has shown to be more effective than hydroxychloroquine in treating coronavirus patients. https://techstartups.com/2020/03/18/breaking-controlled-clinical-study-conducted-doctors-in-france-shows-hydroxychloroquine-cures-100-coronavirus-patients-within-6-days-treatment-covidtrial-io/ That being said, there’s some growing skepticism of the French medical community.
Yeh, I certainly would not want to see the general public taking it prophylactically even if the supply is unlimited some day. That is a prescription for disaster. The minute you put an antibiotic or anti-viral in your body, all the little bugs in your system immediately start to figure out how to do workarounds and they are plenty good at it. And widespread use just creates all sorts of drug-resistant conditions. Better to leave those little fuckers alone and then hammer them hard when you know you are testing positive. You know one of the reasons why physicians always enforce the idea that you must take your antibiotic, antiviral, whatever all the way to the end of the prescribed period is because so many people stop when they feel better- except bacteria or virus are still present. Then the survivors replicate and rise up and they are plenty tough mothers who have learned to survive in the presence of the drug. Rinse and repeat and you suddenly have drug resistance "visitors." I hear ya on the needing enough for immunity thing, but if I am testing positive and the test is good, the little buggers are there and so antibodies are being created and if they are not well then, that is not good either. As I said before, I have a battlefield medicine approach to some of this. Do what gets you to live through this first phase/couple months. If you have a recurrence and need more antibodies those treatments - via infusion or whatever- are out there right now but not any reasonable availabiliity unless you are in a trial. Live a couple more months, after it is fully approved and distributed and it is another arrow in your quiver.
https://www.dailymail.co.uk/news/ar...cessfully-treated-HIV-malaria-medication.html Has Australia found a coronavirus cure? Patients in secret trials are successfully treated with HIV and malaria medication - and now it will be rolled out nationwide A group of patients who were among the first in Australia with confirmed cases of coronavirus have been successfully treated using two existing drugs. They were given HIV medication Kaletra and malaria treatment hydroxychloroquine in a secret trial. The test was so successful that the same drugs will now be given to COVID-19 patients in 50 hospitals around Australia.