Hydroxychloroquine plus azithromycin: a potential interest in reducing in-hospital morbidity due to COVID-19 pneumonia (HI-ZY-COVID)? Abstract Introduction: Hydroxychloroquine (HCQ) with or without azithromycin is currently still debated as a potential treatment for the COVID-19 epidemic. Some studies showed discrepant results. However, timing for the treatment initiation and its setting (in-hospital or out-patient) are not consistent across studies. Methods: Monocentric retrospective study conducted from 2th March to 17th April 2020, in adults hospitalized in a tertiary hospital for COVID-19. Patients characteristics were compared between groups depending on the therapy received (HCQ/azithromycin taken ≥ 48 hours or other treatment). Outcomes were evaluated from admission, by the need for intensive care unit (ICU) support and/or death. Univariate analyses were performed using non-parametric tests and confirmed by a multiple logistic regression using Pearson correlation test. Results: Among 132 patients admitted for COVID-19 in the medicine ward, 45 received HCQ/azithromycin ≥ 48 hours, with a favorable outcome in 91.1% of cases (OR=6.2, p=0.002) versus others regimen (n=87). Groups were comparable at the baseline in terms of age, sex, comorbidities, extend in thoracic imaging, and severity. Among patients that required to be transferred to ICU (n=27) (for mechanical ventilation), median delay for transfer was 2 days (IQR 1-3). We report only 1 patient that presented an adverse event (a prolonged QT interval on EKG) that required to discontinue HCQ. Conclusion: The present study suggests a potential interest of the combination therapy using HCQ/azithromycin for the treatment of COVID-19 in in-hospital patients. And so on, and so on...I've got others.
Cool story, Bro! Have you heard about Joseph Fair MD. He's on NBC a lot. 50yo and hospitalized with this COVID-19 flu.
We may not get to see things go horribly wrong.... possibly only moderately wrong. This is because that the large majority of the people in Georgia are still following stay-at-home and social distancing guidelines. That is the only thing holding the line between moderately wrong and horribly wrong. The fact that Georgia put out data showing COVID-19 cases going down in recent weeks when the number of cases is actually flat or rising --- and apparently did this deliberately with political motivations since this type of error is not merely a "mistake" --- is the the real problem facing Georgia. If politicians are deliberately under-counting the number of cases and deaths from COVID-19 to drive the optics their political agenda then we are nothing more than a third world circus republic.
Hey, I'm just responding to your comment about how things were about to go horribly wrong in Georgia due to their governor. Now you're moving the goal posts. Must be more of that "adaptive modeling".
I responded to why things are not going horribly wrong. It is because 70% of the population of the state are refusing to go to the restaurants, etc. that the governor opened to early. Of course, the slows the economic recovery of the state since nearly no one trusts what the state is doing -- and nearly all don't believe what has been done is in the best interests of public health. As noted by legislators in Georgia, the citizens of the state are merely sacrificial lambs to be thrown under the the governor's political agenda. An agenda so bad that even Donald Trump called Kemp out for it.
Can I ask where you get that 70% of the population is refusing to go to restaurants, etc.? So if the citizens are all sacrificial lambs, does it count if the lambs actually never get sacrificed? Adaptive modeling for the win!
You mean the governor's "adaptive modeling" where he fakes all the data to show a decline. Opinion: Georgia’s coronavirus data made reopening look safe. The numbers were a lie https://www.latimes.com/opinion/sto...numbers-reopening-manipulated-data-brian-kemp
The only Governor who is trusted less than Trump -- meet Georgia's governor Brian Kemp. 49 of 50 governors have better coronavirus poll numbers than Trump https://www.washingtonpost.com/poli...s-have-better-coronavirus-numbers-than-trump/