If anyone you care about has severe refractory ('untreatable') depression problems, this is the single most important thing you'll ever read. This is what antibiotics are to pneumonia, and what insulin is to diabetes. (Two other priceless gifts to humanity from people of Jewish ethnicity.) It will sound crazy. It will sound ridiculous, even impossible... but every word is true. I'll even post a poll to watch how the majority of common fools will reject our scientific discoveries outright. If my knowledge was common knowledge (and it will be, inevitably, within the next 10-20 years.... At least in free societies, which may exclude the new Amerika.) suicide rates would PLUMMET. Incurable depression is now, in most cases, easily cured. THIS is undeniably, THE FUTURE of refractory depression treatment. I am one of the few who know. Here is the simplest possible summary, in layman's terms. I had to figure out all this out for myself, getting zero help from all the fucking worthless medical professionals who treated me....: Everybody in the world has naturally occurring chemicals in their brain called endorphins. Endorphins are nearly identical to (narcotic) opiates like Morphine & heroin, but especially oxycodone. Believe it or not, your own body's endorphins are 48 times more powerful than heroin. We all need endorphins to regulate mood, and keep from getting intolerably depressed. Some people, like myself, have an endorphin deficiency. This is a torturous, often fatal condition... but can be easily cured. We merely need to take endorphins (=opiates) from an external source to feel 'normal' like everyone else. I don't have a drug problem, I have a drug solution. Oxycontin works, but a much safer opioid called buprenorphine is a preferable treatment for many reasons. Now comes the proof: This is from the website of an actual American clinic with branches in three cities. http://www.thepainmanagementcenter.com/english/buprenorphine/clinical.htm "Underproduction or over-removal (severe re-uptake) of these endogenous opioids can be the cause of many psychiatric disorders ranging from Bipolar Personality disorders to major depressive disorders that often times manifest themselves in severe drug abuse.<b> Unbeknownst to them, these patients use opioid medications either illicit or pharmaceutical because they are compelled to attempt to replace the endorphins, dynorphins, and enkephalins (endogenous opioids) that naturally occur in their systems at insufficient levels."</b> Want more proof? You got it: Buprenorphine Treatment of Refractory Depression J. Alexander Bodkin, MD, Gwen L. Zornberg, MD, Scott E. Lukas, PhD, and Jonathan O. Cole, MD. Journal of Clinical Psychopharmacology, 1995, 15, pp. 49-57 Abstract Opiates were used to treat major depression until the mid-1950s. The advent of opioids with mixed agonist-antagonist or partial agonist activity, with reduced dependence and abuse liabilities, has made possible the reevaluation of opioids for this indication. This is of potential importance for the population of depressed patients who are unresponsive to or intolerant of conventional antidepressant agents. Ten subjects with treatment-refractory, unipolar, non-psychotic, major depression were treated with the opioid partial agonist buprenorphine in an open-label study. Three subjects were unable to tolerate more than two doses because of side-effects including malaise, nausea and dysphoria. The remaining seven completed 4 to 6 weeks of treatment and as a group showed clinically striking improvement in both subjective and objective measures of depression. Much of this improvement was observed by the end of 1 week of treatment and persisted throughout the trial. Four subjects achieved complete remission of symptoms by the end of the trial (Hamilton Rating Scale for Depression scores < 6), two were moderately improved, and one deteriorated. These findings suggest a possible role for buprenorphine in treating refractory depression. Introduction Throughout history, opium and its derivatives have had an important role in the pharmacologic treatment of various behavioral disorders and by 1850 were considered to be specific treatments for melancholia (1). At the turn of the century, the eminent authority Emil Kraepelin recommended tincture of opium for the acute treatment of agitated depression(2). This use of opium and its derivatives continued to be recommended in psychiatric textbooks until as recently as 1956(3). However, before the development of modern methods of treatment evaluation, opiate treatment was replaced by somatic treatments such as electroconvulsive therapy and later by monoamine oxidase inhibitors and tricyclic antidepressants. These proved to be effective treatments that lacked the opiates' potential for abuse...Thus, the historically recognized antidepressant properties of the opiates have, with a few exceptions(4-8), received little empirical evaluation. Currently used antidepressants, all of which act on monoaminergic systems, are neither universally effective nor free from adverse effects of their own(9). For the benefit of patients unresponsive to or intolerant of these agents, who may constitute 10 to 30% of the population of patients with major depression(10), alternative drug treatments need to be evaluated. Now, with the development of opioid partial agonist and mixed agonist-antagonist drugs exhibiting much reduced abuse and dependence liabilities,(11) it has become possible to safely evaluate the antidepressant efficacy of opioids. Read the rest if you want the knowledge: http://www.drugbuyers.com/freeboard/showflat.php?Cat=0&Number=196682
A friend of mine suffers from depression. And he makes the best he can out of it...I'm sure he is following your steps or something close... Be happy
You kick ass, Rearden. Good luck with your illness. From personal experience, I can tell you that you yourself are far more likely to find a lasting cure for whatever ails you. No doctor cares about your wellbeing as much as you do. They just want to churn patients in and out of their office as fast as possible to make maximum coin. Also, if I may make a suggestion. If you haven't had one yet, I recommend getting a live blood analysis. I got one from a lady who works at the local health food store. I went intending to prove that she was a scammer, so I didn't talk to her, smile, or wear anything distinguishing in case she could read people like a poker player or Sherlock Holmes, but she was very accurate and pointed out (on her monitor) specific traits of my blood cells which explained my various health problems. Some of my health problems have no visible symptoms at all, but she still knew about them and she explained how she knew. The medical profession doesn't seem too impressed by live blood analysis (they're the competition), but the lady did more to help me than the so-called professionals, and it wasn't a "black box" diagnosis like my doctor makes -- she pointed things out on the screen and referred me to her blood textbook to allow me to agree with her diagnosis or not based on what I saw on the slide. Plus she looks a lot healthier than my doctor. It's worth the 50 bucks or whatever to give it a shot anyway.
We are learning about this in Psychology....Awesome post, great stuff! I hope all goes well for you! -Kastro
This post reads like it was written by a bipolar manic depressive in the euphorically hopeful grandiose manic stage.
The problem with opiates is that they are highly addictive, (but effective). Anti-depressants apparently aren't addictive (but don't work).
Thanx alot cable! I'll have to look into the live blood analysis thing. I definitely agree that any intelligent person is his/her own best doctor. I can provide so many examples, but here's a recent one: A couple weeks ago I started suffering unbearable pain in my left ear. I mean, really nasty pain that persisted despite all the oxy (powerful pain reliever, among other things) that you know I'm always on . Going to a doctor didn't even cross my mind. Using some of the antibiotics in my extensive pharmacological stash was an option, but only if pain (possible bacterial infection) didn't clear up after a few days. Long story short, after a few days of this I figured out independently out that the 'ear' pain was really TJM pain, which is the joint where the jaw meets the ear, and that it was entirely caused by the fact that I had a habit of sitting with my head propped on my left hand when at a computer (much of my day). Anyone else with the same issue could have gone to 20 different ENT 'specialists' and odds are the doctors wouldn't have a clue how to fix the problem. If you are reasonably intelligent, <b>you are your own best doctor.</b>
Yes, most of them are. Buprenorphine, not so much. Besides, anyone with refractory depression resulting from endorphin deficiency, <b>has no choice but to be addicted to opiates</b> Getting us 'clean' is getting us dead. I know it's an iconoclastic concept that not all 'drug abuse' is unhealthy, but in a decade or two it will be common knowledge among medical professionals that what I'm telling you today is 100% correct.
Yes, it does. I know you'd like me alot more if I just called myself 'disabled', and become weak, helpless, and dependant upon the government for my survival. You know, many on the far-left are bleeding hearts with good intentions, but some are just plain old assholes like you. Your problem is that when you look at someone like Stephen Hawking, you point and say "Ha ha! you can't even walk or talk right... what a wimp!"... while I see a brilliant mind. You look at someone like Howard Hughes and laugh at a man you think is a mentally ill freak... while I see a gifted pioneer. You can look at an ingenious scientist and author like Aristotle. A multi-talented mind of the ancient world who paved the way for modern anatomy, astronomy, embryology, geography, geology, meteorology, physics and zoology... yet all you can see is a funny fag who took it up the ass. Ha Ha Ha... but the joke's on you.
When I was in Thailand I met a hill-tribe guy who was an opium addict. His father was 81 and had been doing opium everyday since he was young. But the guy looked older than his 45 years, and sufferred from headaches- I think a fairly common problem with opium addiction.