JAN 10 PROOF OF CONCEPT- Absci first to create, validate de novo antibodies with zero-shot generative AI 01/10/23 ABSI Absci announced the ability to create and validate de novo antibodies in silico with the use of zero-shot generative AI - a major milestone for the biotechnology industry. The ability to create de novo therapeutic antibodies in silico could potentially reduce the time it takes to get new drug leads into the clinic from as much as six years down to just 18-24 months while also increasing their probability of success in the clinic. Absci used zero-shot generative AI - a method that involves designing antibodies to bind to specific targets without using any training data of antibodies known to bind those specific targets. Absci's model produced antibody designs that were unlike those found in existing antibody databases, and the zero-shot designs worked in the lab right out of the computer - without the slow and costly step of further optimizing the in silico designs in the lab. "Despite the technological breakthroughs of the last decade, the process of drug discovery has remained relatively archaic. Our success in creating brand new antibodies on a computer unlocks the potential to create transformative therapies at a click of a button for patients," said Sean McClain, founder and CEO of Absci. "Generative AI used in conjunction with innovative synthetic biology can now be harnessed to have real-world impacts for patients." Absci further demonstrated its wet lab's ability to experimentally validate the superiority of de novo antibody candidates to bind to the target antigen - all without lead optimization of the in silico designs - in cycle times as little as six weeks. Absci validated antibodies for HER2 and multiple additional targets.
NEarly $1 billion in deposits into its new high-yield savings account in just four days, according to a Forbes report. The iPhone maker launched a HYSA last month, offering its Apple Card customers a 4.15% yield. On the first day of launch, Apple gained nearly $400 million in deposits. Apple's high-yield savings account attracted as much as $990 million in deposits in the first four days of its launch, according to a report from Forbes. The successful launch helped underscore Apple's ability to further monetize its iPhone user base of more than 1 billion people. On the first day alone, Apple's new savings account attracted nearly $400 million in deposits, according to the report, which cited two sources familiar with the matter. With more than 240,000 high-yield savings accounts having been opened in the first four days of launch, that represents just 0.2% of Apple's US iPhone users, based on estimates that there are about 120 million of them. Apple launched a high-yield savings account last month/////// APPLE HAS LOW KEYED THIS FOR OBVIOUS REASONS. I DID NOT EVEN KNOW ABOUT THE PRODUCT. THEY HOLD YOUR MONEY LIKE A BANK ACCOUNT? AND CAN APPLE THEN USE IT AS THEY LIKE (BORROW) ?
PAPA JOHN ON THE WIRE-- LOUISVILLE, Ky., May 04, 2023--(BUSINESS WIRE)--Papa John’s International, Inc. (NASDAQ: PZZA) ("Papa Johns®") today announced financial results for the first quarter ended March 26, 2023. Highlights North America comparable sales were flat lapping last year’s record first quarter sales as menu innovation and operational efficiencies drove 3% growth in Domestic Company-owned Restaurants; International comparable sales were down 6% from a year ago primarily due to continued economic pressure in the UK.
UPDATE--- As you know GBA went ST negative on the market April 20. This proved to be smart. We maintain that position although we still hunt for good ideas and trades. ~si
666 is the devil. It's also the all time low for Peloton. The stock is down in the pre market pretty good... At some point i wonder if a Dicks or that other big 5 sports play.. or Hibb takes arun at this company. (I'm not up to date on debt- which I am sure is terrible) Peloton sees Q4 gross margin up 41% q/q driven by shift to subscription revenue 08:52 PTON
Peloton Interactive, Inc. (PTON) NasdaqGS - NasdaqGS Real Time Price. 8.83+0.22 (+2.56%) At close: May 3 04:00PM EDT 7.70 -1.13 (-12.80%) <---------- Tempting Pre-Market: -
I don't entirely understand this: Peloton: Hospitality deals a 'fruitful' source of consumer demand 08:48 PTON Does this mean sales to hotels?