For the dumb Ivermectin cultists

Cuddles · Aug 18, 2022

gwb-trading said:
Ivermectin among generic drugs that failed to help COVID-19 patients avoid hospitalization, large study shows
https://www.msn.com/en-us/health/me...-large-study-shows/ar-AA10M7Zt?ocid=bingcovid

A new study found three generic drugs — fluvoxamine, which is often prescribed to treat depression, the controversial antimalarial ivermectin, and the diabetes pill metformin — failed to prevent the kind of severe COVID-19 that leads to an emergency-room visit or hospitalization.

The research, published Wednesday in The New England Journal of Medicine, examined whether any of the three medications benefited 1,323 patients when prescribed in the early days of a COVID-19 infection. Some of the study’s participants received a combination of metformin and fluvoxamine or metformin and ivermectin, most were vaccinated, and all were overweight. The randomized, placebo-controlled, Phase 3 study was conducted from December 2020 January of this year by researchers at the University of Minnesota.

“None of the medications showed any impact on the primary outcome, which included experiencing low oxygen as measured on an home oxygen monitor,” said Dr. Carolyn Bramonte, principal investigator of the study and an assistant professor of internal medicine and pediatrics at the University of Minnesota Medical School.

Having low blood oxygen levels, or hypoxemia, is a common reason why COVID-19 patients end up seeking care in an ER, being hospitalized, or dying.

Until the Food and Drug Administration authorized Pfizer’s antiviral Paxlovid and Merck’s Lagevrio in late 2021, there were no authorized treatments for people who had tested positive for the virus but were not yet sick enough to go to the hospital. Repurposed drugs — which are cheap, readily available, and have decades of safety data, including among children and pregnant women — have held a particular appeal for regulators and clinicians alike since the pandemic’s earliest days.

Each of the three generic medications has been held up as a possible COVID-19 drug, particularly ivermectin, which gained a cult following over the course of the pandemic despite well-documented issues with the flawed science that in some cases fraudulently touted the drug’s benefits. Yet none so far have demonstrated in robust clinical trials that they actually help treat people with COVID-19.

A long-awaited double-blind, randomized, placebo-controlled study conducted by Duke University School of Medicine and funded by the U.S. concluded in June that ivermectin did not improve symptom duration among COVID-19 patients with mild-to-moderate forms of the disease. The same research found that the drug did not reduce hospitalizations or death.

Some of the same University of Minnesota researchers last year asked the FDA to authorize fluvoxamine as a COVID-19 treatment, based on an earlier set of clinical data. The regulator declined to grant the emergency authorization this spring, saying that the data did not demonstrate the drug’s ability to treat COVID-19.

There is one possible bright spot in the study’s findings, at least for metformin. When the researchers looked at the study’s secondary endpoints, they found that metformin reduced ER visits, hospitalization, or death by 40%, even though the pill doesn’t show an impact on hypoxemia. That said, the researchers say additional studies need to be conducted before clinicians begin prescribing metformin to their COVID-19 patients.

“We’re really happy that our study is adding to the knowledge that we’re gaining around this pandemic in this virus,” Bramonte said. “At this point, there may be physicians who see our results and see metformin as providing easily accessible treatments for certain patients. However, as a physician researcher, I see there’s a need for further study to replicate these results as the primary outcome of a study.”
More...

stopped reading at "antimalarial ivermectin"

gwb-trading · Sep 13, 2022

Russell Brand Tries to Promote Ivermectin, Gets Instantly Fact-Checked by His Own Followers
https://www.vice.com/en/article/z34zd9/russell-brand-ivermectin

gwb-trading · Oct 25, 2022

Yet another study shows that Ivermectin is worthless for treating Covid.

Ivermectin — a drug once touted as a Covid treatment by conservatives — doesn’t improve recovery much, clinical trial finds
https://www.cnbc.com/2022/10/24/ive...prove-recovery-much-clinical-trial-finds.html

A team of scientists affiliated with Duke University found that ivermectin does not meaningfully improve the recovery of people with mild to moderate Covid.

“These findings do not support the use of ivermectin in patients with mild to moderate COVID-19,” they concluded.

A previous study found that ivermectin does not lower the risk of hospitalization from Covid.

The FDA has warned people against taking the tablets for anything other than their approved use.

Ivermectin, a drug once touted by conservatives as a treatment for Covid, does not meaningfully improve the recovery time for people with mild to moderate cases, according a large clinical trial published in a peer-reviewed journal.

People who took ivermectin recovered from Covid in 12 days while people who didn’t take the drug recovered in 13 days, according to the study published in the Journal of the American Medical Association on Friday. Ivermectin has been approved to treat parasitic worms in humans, but it’s primarily used as a dewormer for horses.

“Among outpatients with mild to moderate COVID-19, treatment with ivermectin, compared with placebo, did not significantly improve time to recovery,” the team of scientists led by Duke University School of Medicine wrote. “These findings do not support the use of ivermectin in patients with mild to moderate COVID-19,” they concluded.

Early on in the pandemic when there were few treatment options, ivermectin gained national notoriety when a couple groups of conservative doctors, including Front Line COVID-19 Critical Care Alliance and America’s Frontline Doctors began touting the drug on social media and elsewhere as a treatment for Covid. But there was little data backing up those claims and a study by Dr. Pierre Kory, a critical care physician in Wisconsin and president of the critical care alliance, claiming it was an effective treatment was later retracted for having flawed data.

The latest trial looked at 817 people who took ivermectin tablets for three days and compared them to 774 who received a placebo. The participants who took ivermectin received a daily dose based on their weight. Recovery from Covid was defined as three consecutive days without symptoms.

One person died in the ivermectin group while not one person who received the placebo passed away. The number of people hospitalized in each group was the same at nine participants each.

The study was conducted across 93 sites in the U.S. from June 2021 through May 2022 when the delta variant and then the omicron variant were dominant.

The Food and Drug Administration has not authorized ivermectin for treating or preventing Covid and has repeatedly warned people against taking the drug for anything other than its approved purpose.

Public interest in ivermectin spiked early in the pandemic when a lab study indicated that the drug slowed replication of the virus that causes Covid in a petri dish. But several trials have now found that the ivermectin does not provide any meaningful benefit for patients against Covid.

A study in the New England Journal of Medicine, published in May, found that ivermectin did not lower the risk of hospitalization from Covid.

Ivermectin is approved in the U.S. in a liquid or paste form to treat parasites in animals. There is also a tablet version that is FDA approved to treat parasitic worms, head lice and some skin conditions in people.

“There’s a lot of misinformation around, and you may have heard that it’s okay to take large doses of ivermectin. It is not okay,” the FDA says on its website, warning people that they could overdose.

The drug regulator also sternly warned people against taking ivermectin formulations designed for animals such as horses and cows.

“For one thing, animal drugs are often highly concentrated because they are used for large animals like horses and cows, which weigh a lot more than we do— up to a ton or more. Such high doses can be highly toxic in humans,” the FDA says.

Cuddles · Oct 29, 2022

gwb-trading · Nov 30, 2022

Great News Cultists.

They have found out Ivermectin is effective...

... Against bedbugs with chickens.

Common veterinary drugs show effectiveness against bed bugs
https://phys.org/news/2022-11-common-veterinary-drugs-effectiveness-bed.html

Two common drugs used by veterinarians to combat parasites may be effective against bed bugs, with one showing especially strong potential, according to a new study from North Carolina State University that examined the drugs in the context of controlling resurgent bed bug populations on poultry farms.

Fluralaner and ivermectin, which are used to kill fleas and ticks on household pets like dogs and cats, among other uses, were tested for their effectiveness in killing bed bugs. In a collaboration between entomologists and veterinary scientists from NC State's College of Veterinary Medicine, researchers tested bed bug mortality rates in different experiments: after the pests consumed blood mixed with the drugs on the lab bench and after bed bugs bit and fed off chickens that had either ingested or received topical treatment with the drugs.

(More at above url)

easymon1 · Dec 6, 2022

Peer Review Studies, any day not.

gwb-trading · Jan 28, 2023

Finally state medical boards are taking actions against doctors who improperly pushed Ivermectin as a cure for Covid. Long overdue.

Colorado doctor admits "unprofessional conduct" in giving ivermectin to COVID-19 patients
https://www.cbsnews.com/colorado/ne...tor-unprofessional-conduct-covid-19-patients/

The Colorado Medical Board has disciplined a family physician in western Colorado, Dr. Scott Eric Rollins, for prescribing ivermectin to three of his patients without properly informing them of the risks, and without discussing FDA approved COVID-19 treatments. Ivermectin is not FDA approved for use on humans to address COVID-19.

Rollins, whose practice is in Grand Junction, admitted to "unprofessional conduct" and agreed that his medical license would be placed on indefinite probation until he complies with terms laid out by the medical board.

Rollins did not respond to multiple calls and electronic messages sent by CBS News Colorado. On Friday afternoon his office manager called back and said "he is out of the office today."

Ivermectin is used in the U.S to treat or prevent parasites in animals. For humans, ivermectin tablets are used to treat some parasitic worms and it has been used to treat heat lice and skin conditions. During the height of the pandemic, ivermectin was ballyhooed in some quarters as a "miracle cure" for COVID-19.

But the Food and Drug Administration has not approved ivermectin for treating or preventing COVID-19 in humans and the agency says it can be dangerous for humans to take large doses of ivermectin. The Mayo Clinic said of ivermectin, "Ivermectin isn't a drug for treating viruses. The FDA hasn't approved use of this drug to treat or prevent COVID-19. Taking large doses of this drug can cause serious harm. Don't use medications intended for animals on yourself."

The Colorado Medical Board said Rollins failed to document or discuss with the patients using FDA approved treatments for COVID-19, failed to document or discuss "perceived benefits of prescribing ivermectin."

Several clinical trials have concluded that ivermectin is not effective in addressing COVID-19. The FDA said in 2022, "The primary outcomes of these trials showed that the use of ivermectin for the treatment of COVID-19 had no clinical benefit."

Dr. Rollins has held a Colorado medical license since 1993.

easymon1 · Feb 6, 2023

easymon1 · Feb 9, 2023

gwb-trading · Feb 13, 2023

Please welcome the highly infectious Marburg virus. It makes you bleed from every orifice and has a fatality rate of up to 88%. But the Covid-deniers say it's just a little flu... that Ivermectin will cure... since this outbreak is currently in Africa. Remember the Covid-deniers claim that Hydroxy and Ivermectin wiped out Covid in Africa -- vaccines had nothing to do with it.

Equatorial Guinea confirms first-ever Marburg virus disease outbreak
https://www.afro.who.int/countries/...rms-first-ever-marburg-virus-disease-outbreak