For the dumb Ivermectin cultists

Discussion in 'Politics' started by gwb-trading, Aug 6, 2021.

  1. gwb-trading

    gwb-trading

    LOL -- Your source is Dr. Simone Gold who is a January 6th insurrectionist and belongs to a group which promotes demon sperm.
     
    #21     Aug 12, 2021
  2. gwb-trading

    gwb-trading

    More details on this study... it's hard to believe that people are stupid enough to be ingesting horse paste trying to believe it cures COVID.

    Major study of Ivermectin, the anti-vaccine crowd’s latest COVID drug, finds ‘no effect whatsoever’
    https://www.latimes.com/business/story/2021-08-11/ivermectin-no-effect-covid

    Ivermectin, the latest supposed treatment for COVID-19 being touted by anti-vaccination groups, had “no effect whatsoever” on the disease, according to a large patient study.

    That’s the conclusion of the Together Trial, which has subjected several purported nonvaccine treatments for COVID-19 to carefully designed clinical testing. The trial is supervised by McMaster University in Hamilton, Canada, and conducted in Brazil.

    One of the trial’s principal investigators, Edward Mills of McMaster, presented the results from the Ivermectin arms of the study at an Aug. 6 symposium sponsored by the National Institutes of Health.

    Among the 1,500 patients in the study, he said, Ivermectin showed “no effect whatsoever” on the trial’s outcome goals — whether patients required extended observation in the emergency room or hospitalization.

    “In our specific trial,” he said, “we do not see the treatment benefit that a lot of the advocates believe should have been” seen.

    The study’s results on Ivermectin haven’t been formally published or peer-reviewed. Earlier peer-reviewed results from the Together Trial related to the antimalarial drug hydroxychloroquine, which had been touted as a miracle treatment for COVID by then-President Trump, were published in April; they showed no significant therapeutic effect on the virus.

    The findings on Ivermectin are yet another blow for advocates promoting the drug as a magic bullet against COVID-19. Ivermectin was developed as a treatment for parasitical diseases, mostly for veterinarians, though it’s also used against some human parasites.

    Its repurposing as a COVID treatment began with a 2020 paper by Australian researchers who determined that at extremely high concentrations it showed some efficacy against the SARS-CoV-2 virus, which causes COVID, in the lab. But their research involved concentrations of the drug far beyond what could be achieved, much less tolerated, in the human body.

    [​IMG]

    The Ivermectin camp, as I reported earlier, is heavily peopled by anti-vaccination advocates and conspiracy mongers. They maintain that the truth about the drug has been suppressed by agents of the pharmaceutical industry, which ostensibly prefers to collect the more generous profits that will flow from COVID vaccines.

    The problem, however, is that the scientific trials cited by Ivermectin advocates have been too small or poorly documented to prove their case. One large trial from Egypt that showed the most significant therapeutic effect was withdrawn from its publishers due to accusations of plagiarism and bogus data.

    Nevertheless, the advocates have continued to press their case — without necessarily observing accepted standards of scientific discourse. During the symposium, Mills complained that serious researchers looking into claims for COVID treatments have faced unprecedented abuse from advocates.

    “I’ve had enough abuse and so have the other clinical trialists doing Ivermectin,” he said. “Others working in this area have been threatened, their families have been threatened, they’ve been defamed,” he said.

    “I can think of no circumstances in the past where this kind of abuse has occurred to clinical trialists,” he added. “We need to figure out a system where we have each others’ backs on these issues, because the abuse that certain individuals have received is shocking.” He referred to “accusations” and “swearing,” though he gave no specific examples.

    Mills said that his team’s Ivermectin trial was altered after advocacy groups complained that it was too modest to achieve the results they expected. The trial originally tested the results from a single Ivermectin dose in January this year, but was later changed to involve one daily dose for three days of 400 micrograms of the drug for every kilogram (about 2.2 pounds) of the patients’ weight, up to 90 kilograms.

    Half the subjects received a placebo tablet. No clinical results were detected at either dosage, Mills said.

    Asked whether he expected further criticism from Ivermectin advocates, he said it was all but inevitable. “The advocacy groups have set themselves up to be able to critique any clinical trial. They’ve already determined that any valid, well-designed critical trial was set up to fail.”
     
    #22     Aug 12, 2021
  3. smallfil

    smallfil

    And here again is one more example, of an extreme liberal hack promoting widespread vaccination yet, Corona Virus keeps rising? At the same time, no mention of Ivermectin which has proven far more effective as the cure for Corona Virus? Too many lives are being lost because of extreme liberal stupidity? Even in poor countries, they are all blind and led by the UN vaccination programs who offer them the vaccines for free to administer to as many as they can yet, Corona Virus spreads and infects more people there too and Ivermectin as a cure, promoted by doctors in poor countries are instead, demonized and threatened.

    https://www.yahoo.com/news/bomb-blew-doctors-texas-grapple-174006750.html
     
    #23     Aug 12, 2021
  4. gwb-trading

    gwb-trading

    As noted in every proper medical study -- Ivermectin has no benefit in the prevention or treatment of COVID.

    It's become laughable how you are pushing this debunked Ivermectin nonsense.
     
    #24     Aug 12, 2021
  5. userque

    userque

    NO IVERMECTIN??!!!

    https://www.beckershospitalreview.c...as-been-given-for-his-covid-19-treatment.html
    8 drugs Trump has been given for his COVID-19 treatment

    Maia Anderson - Monday, October 5th, 2020" rel="nofollow" style="color: rgb(0, 57, 116); font-size: 1em; word-break: normal; padding-left: 0px; padding-right: 0px;"> Print | Email



    Listen

    Since President Donald Trump tested positive for COVID-19 Oct. 1, he has been given a variety of drugs intended to shorten his recovery time and ease symptoms.

    Though no drug has been FDA approved to treat the virus, a handful have shown positive results in clinical trials. The president has been given drugs that are being tested in clinical trials and aren't available to the general public.

    The eight drugs the president reportedly has been given:

    1. Dexamethasone — President Trump was prescribed the steroid dexamethasone, a drug commonly used to treat asthma, rheumatoid arthritis and certain cancer, on Oct. 3. Sean Conley, DO, the president's physician, said the steroid was given to him in response to his blood oxygen levels dropping twice to 93 percent, according to STAT.

      The steroid is typically recommended for hospitalized patients who need oxygen or are on ventilators. A study released in June showed that dexamethasone reduced deaths by one-third for those who had been sick for more than a week and were on mechanical ventilators, but had no impact on patients receiving no respiratory support. The study suggested that the drug may do more harm than good for patients with milder COVID-19 cases, since steroids hamper the body's immune system.

      The drug is typically given to patients with severe COVID-19 to prevent an immune system overreaction. Some experts called it a "major breakthrough" for COVID-19 treatment, as it was the first drug shown to improve survival rates.

    2. Remdesivir — President Trump was given his first dose of remdesivir Oct. 2, and he will be given a five-day course, CNN reported. Remdesivir, made by Gilead (who gave it the brand name of Veklury), was granted emergency use authorization by the FDA on May 1 after a study showed it caused a 31 percent faster recovery time compared to a placebo.

      Remdesivir is an intravenous drug that works by targeting the system coronaviruses use to replicate themselves. It has been previously tested for Ebola, but hasn't been officially approved in any country. The FDA expanded its emergency use authorization for remdesivir Aug. 28, allowing it to be used on all hospitalized patients. It had previously only been authorized for those on ventilators or with low blood oxygen levels.

    3. Regeneron's monoclonal antibody — On Oct. 2, the White House released a letter saying the president received a single 8-gram dose of Regeneron's monoclonal antibody cocktail, called REGN-COV2, the highest dose of the drug being tested in late-stage clinical trials, according to Politico.

      Regeneron said in a Sept. 29 news release that a high dose of the drug caused the level of the virus to decrease in patients in an early clinical trial, indicating it may help COVID-19 patients recover faster. The trial seemed to show the drug had a bigger effect on patients who were infected with the virus but hadn't created high levels of their own antibodies against the virus. The drug uses synthetic versions of the antibodies patients' bodies create when they recover from a disease. In July, Regeneron received $450 million from Operation Warp Speed, the White House's task force to expedite COVID-19 vaccine development, to manufacture thousands of doses of the drug.

      Regeneron CEO Leonard Schleifer, MD, PhD, told The New York Times that President Trump's medical staff reached out to the company for permission to use the drug, and that it was cleared with the FDA. Mr. Schleifer has known the president casually for many years and is a member of his golf club in Westchester County, N.Y., according to the Times.

    4. Zinc — President Trump also has been given zinc, according to the Times, which helps the immune system fight outside bacteria and viruses. Zinc is an essential mineral that is naturally present in some foods and is available as a dietary supplement. There is no evidence that zinc helps fight COVID-19, and the FDA has issued warning letters to some companies that have tried to claim there's a link between zinc products and reduced risk of COVID-19.

    5. Vitamin D — President Trump has been given vitamin D, the Times reported, which is good for bone health. There is no evidence vitamin D directly reduces the risk of COVID-19, and the FDA has sent warning letters to companies trying to sell vitamin D products as COVID-19 treatments. Vitamin D can also help reduce inflammation, according to the National Institutes of Health.

    6. Famotidine — The generic name for Pepcid, famotidine is commonly used to treat ulcers, heartburn, indigestion and reduces the amount of acid in the stomach. A clinical trial testing the drug in hospitalized COVID-19 patients in New York wasn't able to recruit enough patients to properly evaluate its impact, according to Science.

    7. Melatonin — Commonly used to treat insomnia, some studies have suggested that melatonin could also help COVID-19 patients with diabetes and obesity, according to CNN.

      "The ability of melatonin to decrease viral infections in obese and diabetic patients is attributed to its characterists, such as potent antioxidant effects, improving the endogenous antioxidant system, immunomodulatory, and the strong anti-inflammatory capability," according to researchers from Mansoura University in Egypt.

      A health summary for President Trump released in June showed that he was obese, at 244 pounds, the Times reported.

    8. Aspirin — Commonly given to older patients to prevent heart disease, aspirin is also a popular painkiller. It can reduce the risk of blood-clotting, and evidence has shown COVID-19 can trigger blood clots in some patients. The president has mild heart disease, the Times reported.
    More at the top URL
     
    #25     Aug 12, 2021
  6. gwb-trading

    gwb-trading


    No hydroxychloroquine either
     
    #26     Aug 12, 2021
    userque likes this.
  7. gwb-trading

    gwb-trading

    #27     Aug 12, 2021
  8. Wallet

    Wallet

    Use of Ivermectin Is Associated With Lower Mortality in Hospitalized Patients With Coronavirus Disease 2019: The Ivermectin in COVID Nineteen Study



    Interpretation: Ivermectin treatment was associated with lower mortality during treatment of COVID-19, especially in patients with severe pulmonary involvement. Randomized controlled trials are needed to confirm these findings.

    https://pubmed.ncbi.nlm.nih.gov/33065103/
     
    #28     Aug 12, 2021
  9. Cuddles

    Cuddles

    score another point to M4A
     
    #29     Aug 12, 2021
  10. gwb-trading

    gwb-trading

    Ivermectin for the Treatment of Coronavirus Disease 2019: A Systematic Review and Meta-analysis of Randomized Controlled Trials
    https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciab591/6310839


    Abstract

    Background
    We systematically assessed benefits and harms of the use of ivermectin (IVM) in patients with coronavirus disease 2019 (COVID-19).

    Methods
    Published and preprint randomized controlled trials (RCTs) assessing the effects of IVM on adult patients with COVID-19 were searched until 22 March 2021 in 5 engines. Primary outcomes were all-cause mortality rate, length of hospital stay (LOS), and adverse events (AEs). Secondary outcomes included viral clearance and severe AEs (SAEs). The risk of bias (RoB) was evaluated using the Cochrane Risk of Bias 2.0 tool. Inverse variance random effect meta-analyses were performed, with quality of evidence (QoE) evaluated using GRADE methods.

    Results
    Ten RCTs (n = 1173) were included. The controls were the standard of care in 5 RCTs and placebo in 5. COVID-19 disease severity was mild in 8 RCTs, moderate in 1, and mild and moderate in 1. IVM did not reduce all-cause mortality rates compared with controls (relative risk [RR], 0.37 [95% confidence interval, .12–1.13]; very low QoE) or LOS compared with controls (mean difference, 0.72 days [95% confidence interval, −.86 to 2.29 days]; very low QoE). AEs, SAEs, and viral clearance were similar between IVM and control groups (low QoE for all outcomes). Subgroups by severity of COVID-19 or RoB were mostly consistent with main analyses; all-cause mortality rates in 3 RCTs at high RoB were reduced with IVM.

    Conclusions

    Compared with the standard of care or placebo, IVM did not reduce all-cause mortality, LOS, or viral clearance in RCTs in patients with mostly mild COVID-19. IVM did not have an effect on AEs or SAEs and is not a viable option to treat patients with COVID-19.

    (More at above url)


    Effect of Ivermectin on Time to Resolution of Symptoms Among Adults With Mild COVID-19A Randomized Clinical Trial

    https://jamanetwork.com/journals/jama/fullarticle/2777389

    Key Points

    Question What is the effect of ivermectin on duration of symptoms in adults with mild COVID-19?

    Findings In this randomized clinical trial that included 476 patients, the duration of symptoms was not significantly different for patients who received a 5-day course of ivermectin compared with placebo (median time to resolution of symptoms, 10 vs 12 days; hazard ratio for resolution of symptoms, 1.07).

    Meaning The findings do not support the use of ivermectin for treatment of mild COVID-19, although larger trials may be needed to understand effects on other clinically relevant outcomes.

    (More at above url)
     
    #30     Aug 15, 2021