DNA to RNA to Protein

Discussion in 'Science and Technology' started by easymon1, Aug 30, 2019.

  1. easymon1

    easymon1

    As with any potentially powerful technique, gene drives can be misused in a variety of ways or induce unintended consequences.
    Gene drives affect all future generations and represent the possibility of a larger change in a living species than has been possible before.[15]
    https://en.wikipedia.org/wiki/Gene_drive

    Human accelerated regions (HARs), first described in August 2006,[1][2] are a set of 49 segments of the human genome that are conserved throughout vertebrate evolution but are strikingly different in humans. They are named according to their degree of difference between humans and chimpanzees (HAR1 showing the largest degree of human-chimpanzee differences). Found by scanning through genomic databases of multiple species, some of these highly mutated areas may contribute to human-specific traits. Others may represent loss of functional mutations, possibly due to the action of biased gene conversion [2][3] rather than adaptive evolution.
    https://en.wikipedia.org/wiki/Human_accelerated_regions

    Such action at a distance is extremely common in eucaryotic cells, where gene regulatory proteins bound to sequences thousands of nucleotide pairs from the promoter generally control gene expression. Eucaryotic activators and repressors act by a wide variety of mechanisms—generally causing the local modification of chromatin structure, the assembly of the general transcription factors at the promoter, and the recruitment of  RNA polymerase.
    https://www.ncbi.nlm.nih.gov/books/NBK26872/

    https://en.wikipedia.org/wiki/Broad_Institute
     
    Last edited: May 2, 2020
    #11     May 2, 2020
  2. piezoe

    piezoe

    For anyone curious to know why all living organisms and related non-organisms such as viruses are all carbon based and will be everywhere in the Universe, read "Why Life Exists", M.J.S. Dewar and E.F. Healy, in Organometallics 1982, 1, 1705–1708.
     
    #12     May 6, 2020
    dartmus likes this.
  3. easymon1

    easymon1

    got a citation handy?
     
    #13     May 11, 2020
  4. piezoe

    piezoe

    Holy shit! That IS the citation I gave you. To look up the article, that's all you need.
     
    #14     May 12, 2020
  5. easymon1

    easymon1

    Why Life Exists", M.J.S. Dewar and E.F. Healy, in Organometallics 1982, 1, 1705–1708
    yeah, i tried that the first time.
    Did you pay to gain access or what? Thx
    delete why life exists.jpg
     
    #15     May 12, 2020
  6. easymon1

    easymon1

  7. easymon1

    easymon1

  8. wrbtrader

    wrbtrader

    Amazing in that you made this thread back in August 2019 and now that we're in the midst of a Pandemic, talks about Covid-19, talks about vaccinations...people becoming ill, people dying and global economies being devastated...

    Still very little interest by those not interested in science...same people leaving it to scientists and health officials to fix things.

    Anyways, thanks for being interested in DNA / RNA / Proteins.

    wrbtrader
     
    #18     May 24, 2020
    Slope Trader and Ayn Rand like this.
  9. easymon1

    easymon1

  10. easymon1

    easymon1

    Phage display is a laboratory technique for the study of protein–protein, proteinpeptide, and protein–DNA interactions that uses bacteriophages (viruses that infect bacteria) to connect proteins with the genetic information that encodes them.[1] In this technique, a gene encoding a protein of interest is inserted into a phage coat protein gene, causing the phage to "display" the protein on its outside while containing the gene for the protein on its inside, resulting in a connection between genotype and phenotype. These displaying phages can then be screened against other proteins, peptides or DNA sequences, in order to detect interaction between the displayed protein and those other molecules. In this way, large libraries of proteins can be screened and amplified in a process called in vitro selection, which is analogous to natural selection.
    [​IMG]

    https://en.wikipedia.org/wiki/Phage_display

    https://yippy.com/search?query=Phage+display
     
    #20     Aug 3, 2020