No one is anti-vaccine. We are anti-Mandatory Vaccine. We are also against the Leftists/Marxists.Statists that denounce therapeutics.
Ivermectin Shows No Clear Benefit in the Treatment of Covid-19 New trial results find no statistically significant effect https://elemental.medium.com/ivermectin-for-covid-19-an-update-5e913bb49483 Ivermectin is ahorse dewormerand anti-parasitic medication that has been promoted across the world for the treatment of Covid-19. It has been in the news a lot recently because alarge portion of the evidence base for the drugappears to have been based on fraudulent research, which, as scientific rigor goes, is usually considered to be a bit of an issue. But we’ve held out hope that the drugworks for Covid-19 because, despite the foundations of the research being cracked, there were still a number of positive trials, and some of them were really well done. Yes, fraud is bad, but we can’t throw the baby out with the bathwater just because one study may never have happened at all. Until today. The results from a very large new study were just released, showing absolutely no benefit for ivermectin when compared with a placebo pill.It now seems depressingly likely that ivermectin is probably not useful for treating Covid-19. New research The new study in question is called theTogether Clinical Trials, and it’s a truly amazing collaboration between a number of universities and research groups to study the effects of repurposed drugs on people with Covid-19 who attend hospitals as outpatients. Basically, they look at people who are at moderate risk but are experiencing relatively mild disease, randomize them to either get one of several drugs or a placebo, and then see if those drugs have any benefit in treating Covid-19. The full protocol is a masterpiece of science—well worth reading if you’re interested in trial design. This trial has already demonstrated that hydroxychloroquine and lopinavir/ritonavir are unlikely to be beneficial treatments for people with Covid-19 in outpatient settings and, because of the hype around ivermectin, had included the drug in a treatment arm to see if it worked. The results from that part of the trial, including over 1,300 patients, were released in summary form late this afternoon. They showed no benefit for ivermectin in the treatment of Covid-19. None whatsoever. Pictured: Results from the slide deck. Source:Together Clinical Trials Now, it’s worth noting that these are not the final results — the authors have released a slide deck along with a lengthy presentation, but we don’t have an actual published version of the study yet. That being said, the protocol is available online, and the study itself is a very impressive work of science. In a high-quality study of over 1,300 people, the researchers found that giving ivermectin to people who had mild disease did not reduce the risk of hospitalization or death at all. This is the largest and best trial conducted on ivermectin to date. That makes the finding pretty solid and very disappointing for all of us who hoped that ivermectin really was effective against Covid-19. The big picture So these results showed no benefit for ivermectin. That’s very useful, but it raises another question: What does this mean for the ivermectin literature as a whole? I’ve previously written about the ivermectin literature, looking at the meta-analyses of the drug to see what the benefit for mortality is (i.e., how much it reduces the risk of dying). This means that I luckily have a great baseline that can easily be updated to include this new study as well as one other trial that has come out recently on ivermectin and Covid-19. The results are, unfortunately, not very good — ivermectin may offer everything from a modest benefit to a modest harm in the treatment of people with Covid-19. I used the studies from Bryant, et al. and the same model replicated in Stata 15.0, which is an inverse-variance model with random effects. I took out the potentially fraudulent Elgazzar study and extremely low-quality Niaee study and added the newer Vallejos paper as well as the Together Clinical Trials. The numbers on the bottom of that forest plot pretty much say it all — with no heterogeneity, there is no evidence of a benefit for ivermectin on the treatment of Covid-19 in this statistical model. The confidence interval runs from a 43% benefit to a 14% detriment, meaning that ivermectin may either be good for your health or increase your risk of death based on the studies included. I’m still hopeful that ivermectin has some benefit. It’s plausible, based on these results, that the drug reduces the risk of dying by a modest amount (in the range of 10%), which is still a really good intervention even if it’s not the miracle some were hoping for. But it is really not possible to say that with any certainty yet, and the biggest and best trials appear to paint a very depressing picture of ivermectin having no benefit. It’s entirely possible — perhaps even likely — that ivermectin is totally useless in the treatment of Covid-19. Given that the drug has been taken by tens, if not hundreds, of millions of people to treat their Covid-19 worldwide, that’s a really unfortunate finding to be faced with. There is a slight silver lining to this new trial. Fluvoxamine, another cheap repurposed medication, showed quite impressive benefits on the risk of hospitalization. While there was no improvement seen in people’s risk of death, it still points toward fluvoxamine potentially being a very effective treatment for people with early or mild Covid-19, which is a truly fantastic finding. So while we can all commiserate over the fact that ivermectin is looking less and less likely to be effective, we can celebrate both the amazing researchers who’ve done this work and the increasing likelihood that fluvoxamine could actually be a very useful drug for Covid-19. This is the first good trial to show such a benefit, but as I said, it was big and a very solid piece of work, so it’s looking likely that the fluvoxamine is indeed effective just as it’s looking likely that ivermectin is not. As before, it’s still possible that ivermectin works, and I sincerely hope that I’m proven wrong. But as the evidence stands now, it really doesn’t look good.
@Buy1Sell2, Read the thread title of this thread...it uses a typical "Anti-Vaccine" attack. It's anti-vaccine via calling Vaccines a scam. Further, two individuals from outside of North America specifically post anti-vaccine propaganda from other countries involving statistics from other countries... That's Anti-Vaccine. Just as importantly, if this thread was about Anti-Mandates... @carrer and @Van_der_Voort_4 failed to keep their discussions about such. I think @Van_der_Voort_4 tried to talk about such via posting an image / video in another thread about an anti-mandate march in Montreal, Canada but nobody seem to care. My point, neither one of those guys started a thread specifically about anti-mandates because they've been aggressively anti-vaccines as shown via the thread title of this thread and most of their discussions in this thread. You're welcome to start a thread about anti-mandates that want to encourage (force) people to take vaccines. Also, Covid therapeutics are aggressively used in North America hospitals and promoted by our Politicians. Ivermectin is not one of those therapeutics being used in hospitals nor promoted by Politicians... Maybe because that target audience here at Elitetrader.com is primarily North Americans where Ivermectin is not approved. Yet, if most here are from India, Pakistan, Afghanistan, or United Kingdom...Ivermectin use would be a very good discussion here. I've posted earlier a list of approved medical therapeutics by the FDA and commonly used in North American hospitals including a specific list the former President Trump used when he was stricken with Covid infection. Former President Trump did not use Ivermectin the miracle drug...you're more than welcome to explain why ??? Again, I'll repeat that Governor DeSantis is promoting in his state of Florida the therapeutic medical drug called Regeneron. Why is he not promoting Ivermectin the miracle drug ??? If you're really about anti-mandates...use the video below to talk about it...start a thread about it. We gotta keep you honest whenever you show up to bullshit the thread participants. Yeah, there are no Ivermectin signs in the below video. wrbtrader
GWB probably doesn't like foreigners promoting drugs not approved for use in North America by people also bashing vaccines at a North American trading forum in which > 90% of those sick with Covid in North American hospitals have not been vaccinated. Also, North America has its own approved medical drugs / treatments for those ill from a Covid infection. Hospitals here aggressively use these therapeutic drugs / treatments. Ask Trump if you think I'm lying. wrbtrader
Trump: “He’s (Biden) not running government anyway. They have a cabal that runs government. A group of people.” Maria: “Who’s running it, Mr. President? Who do you think is in charge?” Trump: “I don’t want to say right now.”
Before you continue to post fake bullshiat - -you do realize the CDC and FDA are part of the federal Health and Human Services agency which is requiring that its employees & contractors be vaccinated.
COVID-19 Ivermectin Triple Therapy Protocol released to GPs Australian GPs can now legally prescribe the treatment to COVID-19 patients. Triple therapy specialist Professor Thomas Borody has issued a Triple Therapy Protocol (Ivermectin, Zinc and Doxycycline) for COVID-19 to Australian GPs, allowing them to lawfully prescribe the drug to COVID-19 positive patients, or as a potential preventive measure. “The three medications are now on chemist shelves right now and GPs can email GP@CDD.com.au to obtain the dosing protocol and COVID-19 treatment information for their patients,” he said. Prof. Borody, an internationally regarded physician renowned for his groundbreaking triple antibiotic therapy for peptic ulcers in 1987, said that the drug Ivermectin should be actively pursued by the Australian Government. https://www.upstart.net.au/covid-19-ivermectin-triple-therapy-protocol-released-to-gps/
A key quote below is what's stated about Covid therapeutic treatments in the United States of America... The above quote is from the White House to debunk misinformation that they are only promoting vaccines and face mask wear. In fact, they've been encouraging Governors of the states to promote Covid therapeutic treatments. Just as importantly, hospitals in North America (United States and Canada) have been aggressively using different types of approved Covid medical treatments. In fact, its free in Canada and the United States has recently made it free under the Biden administration to remove the stigma that only the rich could afford the Covid therapeutic treatments. In my opinion, its a get out of jail free card for the Covidiots that do not vaccinate and then become infected with Covid Delta Variant. ---------- Demand for COVID antibody drugs soars in hard-hit states People infected with COVID-19 were captured in a photo this week lying on the floor in pain while waiting for antibody infusions at a treatment site set up inside the library in Jacksonville Florida The image has become a vivid illustration of the huge demand for the once-neglected COVID-19 drugs in the states hit hardest by a summer surge of infections being driven by the highly contagious delta variant. "They were moaning and obviously in a lot of pain. They were miserable,” said Luis Lopez, who shot the photograph as he waited for more than two hours to receive the treatment. Antibody treatments remain one of a handful of therapies that can blunt the worst effects of COVID-19, and they are the only option available to people with mild-to-moderate cases who aren’t yet in the hospital. They have risen in demand in states seeing a spike in infections, including Florida, Louisiana and Texas, where hospitalizations among the unvaccinated are overwhelming the health care system. White House officials reported recently that federal shipments of the drugs increased five-fold last month to nearly 110,000 doses, with the vast majority going to states with low vaccination rates. “They are safe, they are free, they keep people out of the hospital and help keep them alive,” said Dr. Marcella Nunez-Smith, a senior adviser to the White House’s COVID-19 response team. The main drug in use is Regeneron’s dual-antibody cocktail, which has been purchased in mass quantities by the U.S. government. It’s the same drug former President Donald Trump received when he was hospitalized with COVID-19 last October. The drugs are laboratory-made versions of virus-blocking antibodies that help fight off infections. The treatments help the patient by supplying concentrated doses of one or two antibodies. The drugs are only recommended for people at the highest risk of progressing to severe COVID-19, but regulators have slowly broadened who can qualify. The list of conditions now includes older age, obesity, diabetes, heart disease, pregnancy and more than a half-dozen other issues. With expanded eligibility and skyrocketing caseloads across the country, more people are getting the treatments. Texas Gov. Greg Abbott who this week tested positive for the virus and is himself receiving the treatments, said five state-run COVID-19 antibody infusion centers opened last week and that another four would open by Monday. At least 140 providers across Texas are offering the antibodies treatment, his office said. In Florida, where more than 20,000 people a day on average are testing positive for the virus, the rising demand created a scene at the Jacksonville center that resembled an overwhelmed emergency room. At one point, Lopez said staff brought out paper hospital gowns and covered a woman on the floor. It took more than half an hour for staff to bring out enough wheelchairs for people to sit in. “They poured them into the wheelchairs,” he said. “They were just so sick.” After the photo was published Wednesday, Florida health officials said they had increased the number of wheelchairs at the facility. They also said it is open seven days a week and has plenty of cots, as well as ambulances on standby to transfer the sickest patients to the hospital. “None of our sites are having a capacity issue,” said Weesam Khoury, spokesperson for the Florida Department of Health. “We have the resources and if we need more we can quickly get them.” But she cautioned, “This is a site where people are going to be very ill.” That’s why state health officials are urging patients who test positive for COVID to get the antibody treatment immediately instead of waiting until they are extremely sick, which many patients are doing. Florida over the past week has set up about a dozen monoclonal antibody clinics typically serving 300 patients per day, with an online portal for appointments, and plans to stand up more, as Gov. Ron DeSantis has traveled around the state to promote them. Getting the drugs involves a number of steps. A positive test for COVID-19 is required, which must be reviewed by a physician or health professional. They then decide whether to recommend an antibody treatment for the patient, which usually means scheduling an appointment at a local administration site. To be effective, the drugs are supposed to be given within 10 days of initial symptoms. That’s the timeframe in which they have been shown to cut rates of hospitalization and death by roughly 70%. Medical experts agreed that the drugs should not be seen as the first line of defense against the virus or a substitute for wearing a mask and getting vaccinated. “I see the monoclonal antibodies as a short-term bridge to get us to the point where enough people are fully vaccinated,” said Dr. James Cutrell of the University of Texas Southwestern Medical Center in Dallas. “We definitely need to keep vaccinating as many people as possible.” Joyce Wachsmuth, of Eau Claire, Wisconsin, and her husband were infected with COVID-19 in January. A breast cancer survivor, she had never felt so much pain. “I actually thought to myself if 10 days of this is what COVID people go thru, I don't know if I want to live,” she said. When doctors at the local Mayo Clinic told the 67-year-old that she and her 70-year-old husband were prime candidates for experimental drug treatment, she jumped at the opportunity. She said she felt relief just two hours after the one-hour, drip treatment. “It did wonders. It kept us off the hospital and off the ventilators,” said Wachsmuth, who has since been vaccinated. The federal government has been distributing monoclonal antibody drugs to the states since last winter but the treatments were underused due to lack of awareness from physicians, low interest among the public and the logistics of setting up areas to give them to patients via IV infusion. Also, persistent testing delays meant many people didn’t even get their results for seven days or longer, and clinics were focused on the upcoming vaccines or managing the winter surge of cases. Since then, many cities have set up alternative locations to administer the drugs and offer vaccines. The treatments are free for most patients, largely because the federal government has been actively involved in securing and distributing them. “There was less urgency at that time — the important thing was to get people vaccinated to crush the curve,” said Dr. Arturo Casadevall of Johns Hopkins University. “But the delta variant has changed the equation." https://apnews.com/article/health-coronavirus-pandemic-ad87808ad28f29c6cb5f1b98e478c6db wrbtrader