The mind has to stay open. Pathetic when posters cant keep politics out of it. For all we know,in 20 years they look back at us,with a myriad of supporting data,wondering why we didnt all just embrace xyz product and improve our quality of life,cure disease etc. Almost impossible to discuss ideas anymore.
If I met Mel Gibson, RFK Jr, Bryan Johnson etc. I'd do my own research by punching them until their face bones shattered and see if the MB in them reduced stroke infarct size and improved neurological function. Methylene blue, NAD+, peptides, cold plunges, biohacking stacks, all are often promoted with breathless enthusiasm, rarely acknowledging: The gap between animal studies and human reality. The tiny sample sizes or absence of trials altogether. The placebo effect (especially in expensive treatments). And the fact that most benefits, if real, are modest. They sell certainty without consequences to them.
Mel Gibson is a puzzle until you know a little about his arch conspiracy theorist father, Hutton Gibson. A bright man, won Jeopardy five times, who also denied the Holocaust based on some back-of-envelope calculations on fuel requirements to cremate bodies. Its a shame that Mel had this easy-certainly maniac push him to ruin his legacy, but possibly inherited. I am still having my blood plasma cleaned as a personal experiment, but I can't say I feel any different with regards energy levels or health. Like anybody trying to be scientific, I'm not looking at my own blood test results, maybe after a year. I just have a doctor monitoring should anything seriously adverse be showing up. I have looked into MB and sure, it has some intersting properties but one step at a time.
It has valid medical usage, like being an antidote to carbon monoxide poisoning and cyanide poisoning. They used to use it as an antimalarial drug. It also turns your brain blue, what is really cool, specially if you die right away. Its Wiki page has a blue brain picture. So I don't mind if people experience with it, after all the positive result can be good for all society. It has its subreddit, I will quote some personal experiences: "I have been taking 2-8mg and can absolutely feel it, almost immediately. It is most perceptible in my eyes, almost like lifting a fog. Everything feels cleaner/clearer. The energy is subtle but it's there. People that seem to think these low doses have to be placebo, frankly don't understand biochemistry...there are tons of drugs that work at 1mg and under 1mg. Additionally I don't see what would prevent it from working immediately, as it's absorbed by your mucous membranes and GI tract, even on its way to your stomach. Is 25mg too high? No, but you may benefit just as much from lower doses. Why jump right to 25mg?" ----------------- "I would agree with this. Started taking 5 drops and felt that was a bit much - jittery energy territory. Dialed it back to 3 drops and that seems to be the right mix of energy/alert. My wife is still at 5 drops and says that's plenty of energy for her, so people are indeed different in their tolerance to MB. Great stuff though - just make sure the MB you consume is high quality."
Why the hate for Bryan Johnson? He has a medical team vouching for the improvements,in my understanding.He is over 2 million dollars in to his experiment which potentially benefits every human,all the while using himself as the guinea pig. If youve ever had a cup of coffee to wake up or sharpen up.If youve ever had a glass of wine to relax or improve your sociability:youre a biohacker.Some people just realise this concept can be pushed much further.
Australians are going to Mexico for this procedure. This is on the extreme (and expensive) side of biohacking. Id be interested in any further results,if you are able to share.
What is the difference between this and plasma donation? If you donate it your body will make up new plasma, assumedly clean one, so it is cheaper (you get paid) to donate?
It comes down to volume and purpose. Plasma donation removes a small amount, your body replaces it, but that’s not the same as clearing everything in circulation. Plasmapheresis, by contrast, processes a large proportion of your plasma, often more than your total plasma volume, in one session. In my case (I’m about 280 lbs and very muscular), I have around 10.5 liters of blood, and plasma makes up roughly 55%, so 5 to 6 liters are processed each time. Think of it like an oil change: draining and topping off a bit of oil each week never gives you clean oil. But draining most of it and replacing it in one go, that’s the kind of deep clean plasmapheresis attempts. @semperfrosty I don't hate Johnson, however I'm not a fan of things like using his son as a donor as frankly, it could encourage criminal operations to abuse young kids for young-to-old therapies. When I was a ranger in Southern Africa there was a horrific belief that one could take health from children. Albinos had a particularly bad time too. A lot of heath nuts are not really different to muti magic believers. I’ve been using plasmapheresis experimentally to track the efficiency of removing specific circulating proteins, ones that my wife is hypersensitive to. Her immune system reacts so aggressively that it was causing vision loss, a symptom of a complex immune disorder that’s typically considered incurable. We’re not claiming a cure, she was stabilised a different way but the early results are promising enough to continue in the hope of significant added benefit. And no, this isn’t a Bryan Johnson-style longevity stunt. That may yield interesting anecdotes, but without proper clinical controls, it’s not rigorous science. I’m approaching this to see if there’s a measurable, repeatable effect and so far, it’s worth paying attention to.