High-Dose Vitamin D May Shift Calories From Fat to Muscle, Reveals Study – Here's What to Know

Discussion in 'Health and Fitness' started by Frederick Foresight, Mar 26, 2025.

  1. A new insight into how your body utilises and stores calories has emerged, and it could be good news

    https://www.menshealth.com/uk/building-muscle/a64284311/vitamin-d-fat-loss/

    Vitamin D has always had a solid rep when it comes to bone health, but new research suggests it may play a deeper role in shaping our bodies — not just keeping them upright. In a new study scientists explored the effects of high doses of vitamin D. Their headline claim? The sunshine vitamin may help your body allocate excess calories toward muscle growth instead of fat storage.

    This is an interesting glimpse into how the body might decide what to do with the calories you eat. Based on the study, the researchers have proposed a new model for calorie allocation, suggesting that your body’s choice between storing energy as fat or using it to build muscle is influenced by two key signals: leptin and myostatin.

    Leptin is produced by fat cells and acts as a kind of 'fullness' signal — the more fat you have, the more leptin you make. Myostatin, on the other hand, is produced by your muscles and serves as a brake on muscle growth.

    The theory goes like this: when your body senses high leptin and low myostatin, it’s more likely to use nutrients to grow and repair muscle. Resistance training helps to lower myostatin temporarily – that’s part of how you make gains. And according to the researchers, vitamin D might play a role here too, by improving leptin sensitivity and dialling down myostatin production.

    This could result in better nutrient partitioning – ie, your calories going more towards muscle growth, rather than fat storage. The study showed that the group with the high-dose of vitamin D gained more strength and muscle without putting on extra fat.

    That’s promising, even if the effects in humans so far have been more modest – mostly showing up in people who are vitamin D deficient. Which, studies show, is most people. So we could chalk this research up to yet another good reason to keep Vit D in your supplement stack.

    This all sounds great, but before we start double-dosing our daily supps, there’s some fine print.

    This conclusion was derived from animal studies – not humans. While some earlier research has shown that vitamin D deficiency in children is linked to slower growth (especially in winter, when sunlight exposure drops), human data on how vitamin D affects adult body composition is still pretty limited.

    So while it a may not be the game-changer the title of the research suggests, it does open the door to new ways we might influence calorie allocation, muscle growth, and fat storage in the future, while also offering another explanation for why some people report to have an easier time gaining muscle and losing fat in the summer, on top of behavioural and environmental cues.
     
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