Is it better to use higher price stocks ($200-$700) for debit spreads because a small % change in your direction would lead to a bigger gain and you haven“t to buy more than one vertical spread (lower commision)?
I don't think it's necessary to have high priced stocks. You can make the strikes closer and you'll have a more steep curve for your payouts. Easy to check out your scenario using an Option Profit calculator, such as this one: https://www.optionsprofitcalculator.com/